(S)-2-tert-butoxycarbonylamino-3-(4-hydroxy-phenyl)-propionic acid cyclopentyl ester

Base Information

Chemical Name:(S)-2-tert-butoxycarbonylamino-3-(4-hydroxy-phenyl)-propionic acid cyclopentyl ester
CAS No.:914452-23-6
Molecular Formula:C₁₉H₂₇NO₅
Molecular Weight:349.427
Hs Code.:

Synonyms:(S)-2-tert-butoxycarbonylamino-3-(4-hydroxy-phenyl)-propionic acid cyclopentyl ester

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Chemical Property of (S)-2-tert-butoxycarbonylamino-3-(4-hydroxy-phenyl)-propionic acid cyclopentyl ester

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Technology Process of (S)-2-tert-butoxycarbonylamino-3-(4-hydroxy-phenyl)-propionic acid cyclopentyl ester

There total 3 articles about (S)-2-tert-butoxycarbonylamino-3-(4-hydroxy-phenyl)-propionic acid cyclopentyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 914452-22-5
(S)-3-(4-benzyloxy-phenyl)-2-tert-butoxycarbonylamino-propionic acid cyclopentyl ester

: 914452-23-6
(S)-2-tert-butoxycarbonylamino-3-(4-hydroxy-phenyl)-propionic acid cyclopentyl ester

Guidance literature:: With hydrogen; palladium 10% on activated carbon; In ethyl acetate; for 30h;

Reference yield:

: 2130-96-3,54784-43-9
O-benzyl-N-tert-butoxycarbonyl-L-tyrosine

: 914452-23-6
(S)-2-tert-butoxycarbonylamino-3-(4-hydroxy-phenyl)-propionic acid cyclopentyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 22 h / 0 - 20 °C

2: hydrogen / palladium 10% on activated carbon / ethyl acetate / 30 h

With dmap; hydrogen; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; palladium 10% on activated carbon; In ethyl acetate; N,N-dimethyl-formamide;

Reference yield:

: 96-41-3
Cyclopentanol

: 914452-23-6
(S)-2-tert-butoxycarbonylamino-3-(4-hydroxy-phenyl)-propionic acid cyclopentyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 22 h / 0 - 20 °C

2: hydrogen / palladium 10% on activated carbon / ethyl acetate / 30 h

With dmap; hydrogen; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; palladium 10% on activated carbon; In ethyl acetate; N,N-dimethyl-formamide;