2,2'-(2,2'-(2,2'-(2,2'-(1,2-phenylenebis(oxy))bis(ethane-2,1-diyl))bis(oxy)bis(ethane-2,1-diyl)) bis(oxy)bis(ethane-2,1-diyl))bis(oxy)diethanol

Base Information

• Chemical Name: 2,2'-(2,2'-(2,2'-(2,2'-(1,2-phenylenebis(oxy))bis(ethane-2,1-diyl))bis(oxy)bis(ethane-2,1-diyl)) bis(oxy)bis(ethane-2,1-diyl))bis(oxy)diethanol
• CAS No.: 176245-16-2
• Molecular Formula: C₂₂H₃₈O₁₀
• Molecular Weight: 462.538
• Mol file: 176245-16-2.mol

Synonyms:2,2'-(2,2'-(2,2'-(2,2'-(1,2-phenylenebis(oxy))bis(ethane-2,1-diyl))bis(oxy)bis(ethane-2,1-diyl)) bis(oxy)bis(ethane-2,1-diyl))bis(oxy)diethanol

Chemical Property of 2,2'-(2,2'-(2,2'-(2,2'-(1,2-phenylenebis(oxy))bis(ethane-2,1-diyl))bis(oxy)bis(ethane-2,1-diyl)) bis(oxy)bis(ethane-2,1-diyl))bis(oxy)diethanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2'-(2,2'-(2,2'-(2,2'-(1,2-phenylenebis(oxy))bis(ethane-2,1-diyl))bis(oxy)bis(ethane-2,1-diyl)) bis(oxy)bis(ethane-2,1-diyl))bis(oxy)diethanol

There total 3 articles about 2,2'-(2,2'-(2,2'-(2,2'-(1,2-phenylenebis(oxy))bis(ethane-2,1-diyl))bis(oxy)bis(ethane-2,1-diyl)) bis(oxy)bis(ethane-2,1-diyl))bis(oxy)diethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

p-toluenesulfonic acid 2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl ester (77544-60-6) + benzene-1,2-diol (120-80-9,19481-10-8,37349-32-9) → 2,2'-(2,2'-(2,2'-(2,2'-(1,2-phenylenebis(oxy))bis(ethane-2,1-diyl))bis(oxy)bis(ethane-2,1-diyl)) bis(oxy)bis(ethane-2,1-diyl))bis(oxy)diethanol (176245-16-2)

Guidance literature:

With potassium carbonate; potassium iodide; In N,N-dimethyl-formamide; at 80 ℃; for 24h; Inert atmosphere; Schlenk technique;

DOI:10.1002/chem.202001510

Reference yield: 64.0%

benzene-1,2-diol (120-80-9,19481-10-8,37349-32-9) + 2-(2-(2-(2-iodoethoxy)ethoxy)ethoxy)ethanol (136399-06-9) → 2,2'-(2,2'-(2,2'-(2,2'-(1,2-phenylenebis(oxy))bis(ethane-2,1-diyl))bis(oxy)bis(ethane-2,1-diyl)) bis(oxy)bis(ethane-2,1-diyl))bis(oxy)diethanol (176245-16-2)

Guidance literature:

With potassium carbonate; In acetone; for 30h; Reflux;

DOI:10.5012/bkcs.2014.35.5.1541

Reference yield:

Tetraethylene glycol (112-60-7) → 2,2'-(2,2'-(2,2'-(2,2'-(1,2-phenylenebis(oxy))bis(ethane-2,1-diyl))bis(oxy)bis(ethane-2,1-diyl)) bis(oxy)bis(ethane-2,1-diyl))bis(oxy)diethanol (176245-16-2)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium hydroxide / tetrahydrofuran; water / 0.5 h / 0 °C

2.1: caesium carbonate / acetonitrile / 0.17 h / Inert atmosphere; Reflux

2.2: 12 h / Inert atmosphere

With caesium carbonate; sodium hydroxide; In tetrahydrofuran; water; acetonitrile;

DOI:10.2174/1570178612666150902235535

upstream raw materials:

p-toluenesulfonic acid 2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl ester

benzene-1,2-diol

2-(2-(2-(2-iodoethoxy)ethoxy)ethoxy)ethanol

Tetraethylene glycol

Downstream raw materials:

C₃₆H₅₀O₁₄S₂

1,2-bis-(2-{2-[2-(2-iodo-ethoxy)-ethoxy]-ethoxy}-ethoxy)-benzene

C₂₈H₄₂O₁₀

[2,17]dibenzo-30-crown-10