EAPB₅₀₃

Base Information

• Chemical Name: EAPB₅₀₃
• CAS No.: 1140627-77-5
• Molecular Formula: C₁₈H₁₆N₄O
• Molecular Weight: 304.351
• Mol file: 1140627-77-5.mol

Synonyms:EAPB₅₀₃

Chemical Property of EAPB₅₀₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of EAPB₅₀₃

There total 6 articles about EAPB₅₀₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

1-bromo-N-methylimidazo[1,2-a]-quinoxalin-4-amine (1140627-75-3) + 3-methoxyphenylboronic acid (10365-98-7,1107579-37-2) → EAPB503 (1140627-77-5)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In 1,2-dimethoxyethane; water; at 140 ℃; for 0.333333h; Microwave irradiation;

DOI:10.1016/j.ejmech.2009.02.007

Reference yield: 90.0%

→ EAPB503 (1140627-77-5)

Guidance literature:

Reference yield:

N-methylimidazo[1,2-a]quinoxalin-4-amine → EAPB503 (1140627-77-5)

Guidance literature:

Multi-step reaction with 2 steps

1: N-Bromosuccinimide / chloroform / 1.5 h / Reflux

2: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / 1,2-dimethoxyethane; water / 140 °C / Microwave irradiation

With N-Bromosuccinimide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In 1,2-dimethoxyethane; chloroform; water; 2: |Suzuki-Miyaura Coupling;

DOI:10.1007/s10895-017-2097-z

upstream raw materials:

1-bromo-N-methylimidazo[1,2-a]-quinoxalin-4-amine

3-methoxyphenylboronic acid

N-(2-Fluorophenyl)-1H-imidazol-2-carboxamide

imidazo[1,2-a]quinoxaline-4-(5H)-one

Downstream raw materials:

EAPB₆₀₃