(R)-5-Benzyloxy-O-(1-phenylbutyl)pentaldehyde oxime

Base Information

• Chemical Name: (R)-5-Benzyloxy-O-(1-phenylbutyl)pentaldehyde oxime
• CAS No.: 260998-30-9
• Molecular Formula: C₂₂H₂₉NO₂
• Molecular Weight: 339.478
• Mol file: 260998-30-9.mol

Synonyms:(R)-5-Benzyloxy-O-(1-phenylbutyl)pentaldehyde oxime

Chemical Property of (R)-5-Benzyloxy-O-(1-phenylbutyl)pentaldehyde oxime

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of (R)-5-Benzyloxy-O-(1-phenylbutyl)pentaldehyde oxime

There total 1 articles about (R)-5-Benzyloxy-O-(1-phenylbutyl)pentaldehyde oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

5-benzyloxy-1-pentanal (78999-24-3) + (R)-(+)-N-(1-phenylbutoxy)phthalimide (197709-54-9) → (R)-5-Benzyloxy-O-(1-phenylbutyl)pentaldehyde oxime (260998-30-9)

Guidance literature:

With hydrazine hydrate; In ethanol; at 20 ℃;

DOI:10.1039/a907186e

Reference yield: 98.0%

1-propylmagnesium chloride (2234-82-4) + (R)-5-Benzyloxy-O-(1-phenylbutyl)pentaldehyde oxime (260998-30-9) → (R)-8-Benzyloxy-N-[(R)-1-phenylbutoxy]octan-4-ylamine (260998-42-3)

Guidance literature:

(R)-5-Benzyloxy-O-(1-phenylbutyl)pentaldehyde oxime; With boron trifluoride diethyl etherate; In diethyl ether; toluene; at -78 ℃; for 0.25h;

1-propylmagnesium chloride; In diethyl ether; toluene; at -78 ℃;

DOI:10.1039/a907186e

Reference yield:

phenyllithium (591-51-5) + (R)-5-Benzyloxy-O-(1-phenylbutyl)pentaldehyde oxime (260998-30-9) → (S)-5-Benzyloxy-1-phenyl-N-[(R)-1-phenylbutoxy]pentylamine + (R)-5-Benzyloxy-1-phenyl-N-[(R)-1-phenylbutoxy]pentylamine

Guidance literature:

(R)-5-Benzyloxy-O-(1-phenylbutyl)pentaldehyde oxime; With boron trifluoride diethyl etherate; In diethyl ether; toluene; at -78 ℃; for 0.25h;

phenyllithium; In diethyl ether; toluene; at -78 ℃; Title compound not separated from byproducts;

DOI:10.1039/a907186e

upstream raw materials:

5-benzyloxy-1-pentanal

(R)-(+)-N-(1-phenylbutoxy)phthalimide

Downstream raw materials:

(R)-8-Benzyloxy-N-[(R)-1-phenylbutoxy]octan-4-ylamine

Refernces