methyl (5S)-6-amino-5-hydroxy-5-[(4-methylphenyl)sulfenylmethyl]-6-oxohexanoate

Base Information

Chemical Name:methyl (5S)-6-amino-5-hydroxy-5-[(4-methylphenyl)sulfenylmethyl]-6-oxohexanoate
CAS No.:1067938-30-0
Molecular Formula:C₁₅H₂₁NO₄S
Molecular Weight:311.402
Hs Code.:

Synonyms:methyl (5S)-6-amino-5-hydroxy-5-[(4-methylphenyl)sulfenylmethyl]-6-oxohexanoate

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Chemical Property of methyl (5S)-6-amino-5-hydroxy-5-[(4-methylphenyl)sulfenylmethyl]-6-oxohexanoate

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Technology Process of methyl (5S)-6-amino-5-hydroxy-5-[(4-methylphenyl)sulfenylmethyl]-6-oxohexanoate

There total 1 articles about methyl (5S)-6-amino-5-hydroxy-5-[(4-methylphenyl)sulfenylmethyl]-6-oxohexanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 1067938-25-3
methyl (5S,SR)-5-cyano-5-hydroxy-6-[(4-methylphenyl)sulfinyl]hexanoate

: 1067938-30-0
methyl (5S)-6-amino-5-hydroxy-5-[(4-methylphenyl)sulfenylmethyl]-6-oxohexanoate

Guidance literature:: methyl (5S,SR)-5-cyano-5-hydroxy-6-[(4-methylphenyl)sulfinyl]hexanoate; With tetrafluoroboric acid; In diethyl ether; dichloromethane; at -78 - 25 ℃;

With sodium iodide; In diethyl ether; dichloromethane; at 25 ℃; for 24h;
DOI:10.1055/s-2008-1067120

Reference yield: 83.0%

: 1067938-30-0
methyl (5S)-6-amino-5-hydroxy-5-[(4-methylphenyl)sulfenylmethyl]-6-oxohexanoate

: (2S)-2-hydroxy-2-[(4-methylphenyl)sulfenylmethyl]hexanedioic acid

Guidance literature:: methyl (5S)-6-amino-5-hydroxy-5-[(4-methylphenyl)sulfenylmethyl]-6-oxohexanoate; With sulfuric acid; In methanol; water; for 48h; Reflux;

With sodium hydroxide; In methanol; water; for 24h; Reflux;
DOI:10.1055/s-2008-1067120