dimethyl 1-phenylvinylboronate

Base Information

• Chemical Name: dimethyl 1-phenylvinylboronate
• CAS No.: 1338250-08-0
• Molecular Formula: C₁₀H₁₃BO₂
• Molecular Weight: 176.023
• Mol file: 1338250-08-0.mol

Synonyms:dimethyl 1-phenylvinylboronate

Chemical Property of dimethyl 1-phenylvinylboronate

Chemical Property:

Purity/Quality:

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Technology Process of dimethyl 1-phenylvinylboronate

There total 1 articles about dimethyl 1-phenylvinylboronate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

Trimethyl borate (121-43-7,63156-11-6) + 1-bromovinylbenzene (98-81-7) → dimethyl 1-phenylvinylboronate (1338250-08-0)

Guidance literature:

1-bromovinylbenzene; With iodine; magnesium; In tetrahydrofuran; at 20 ℃; for 1.5h; Inert atmosphere; Reflux;

Trimethyl borate; In tetrahydrofuran; at -78 - 20 ℃; Inert atmosphere;

DOI:10.1016/j.tetlet.2011.07.141

Reference yield: 72.0%

diazoacetic acid ethyl ester (623-73-4) + dimethyl 1-phenylvinylboronate (1338250-08-0) → ethyl 3-phenyl-3-butenoate (5633-64-7) + ethyl (E)-3-phenylbut-2-enoate (945-93-7,13979-22-1,1504-72-9)

Guidance literature:

dimethyl 1-phenylvinylboronate; With potassium fluoride; (trifluoromethyl)trimethylsilane; In 1,2-dimethoxyethane; at 20 ℃; for 18h; Inert atmosphere;

With chloro-trimethyl-silane; In 1,2-dimethoxyethane; at -20 - -10 ℃; for 0.333333h; Inert atmosphere;

diazoacetic acid ethyl ester; With methanol; In 1,2-dimethoxyethane; at -20 - 20 ℃; for 2h; Inert atmosphere;

DOI:10.1016/j.tetlet.2011.07.141

upstream raw materials:

Trimethyl borate

1-bromovinylbenzene

Downstream raw materials:

ethyl 3-phenyl-3-butenoate

ethyl (E)-3-phenylbut-2-enoate