Technology Process of (S)-5-allyl 1-benzyl 2-(methylamino)pentanedioate hydrochloride
There total 7 articles about (S)-5-allyl 1-benzyl 2-(methylamino)pentanedioate hydrochloride which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: sodium hydrogencarbonate / N,N-dimethyl-formamide / 1 h / 20 °C
1.2: 16 h
2.1: hydrogenchloride / 1,4-dioxane / 1 h
3.1: pyridine / dichloromethane / 15 h / 0 °C
4.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / N,N-dimethyl-formamide / 4 h / 0 - 20 °C
5.1: thiophenol; caesium carbonate / acetonitrile / 16 h / 20 °C
5.2: 0.08 h
With
pyridine; hydrogenchloride; sodium hydrogencarbonate; caesium carbonate; thiophenol; 1,8-diazabicyclo[5.4.0]undec-7-ene;
In
1,4-dioxane; dichloromethane; N,N-dimethyl-formamide; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: sodium hydrogencarbonate / N,N-dimethyl-formamide / 1 h / 20 °C
1.2: 16 h
2.1: hydrogenchloride / 1,4-dioxane / 1 h
3.1: pyridine / dichloromethane / 15 h / 0 °C
4.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / N,N-dimethyl-formamide / 4 h / 0 - 20 °C
5.1: thiophenol; caesium carbonate / acetonitrile / 16 h / 20 °C
5.2: 0.08 h
With
pyridine; hydrogenchloride; sodium hydrogencarbonate; caesium carbonate; thiophenol; 1,8-diazabicyclo[5.4.0]undec-7-ene;
In
1,4-dioxane; dichloromethane; N,N-dimethyl-formamide; acetonitrile;
