Phosphoric acid di-tert-butyl ester 2,4-dibromo-phenyl ester

Base Information

• Chemical Name: Phosphoric acid di-tert-butyl ester 2,4-dibromo-phenyl ester
• CAS No.: 137360-74-8
• Molecular Formula: C₁₄H₂₁Br₂O₄P
• Molecular Weight: 444.1
• Mol file: 137360-74-8.mol

Synonyms:Phosphoric acid di-tert-butyl ester 2,4-dibromo-phenyl ester

Chemical Property of Phosphoric acid di-tert-butyl ester 2,4-dibromo-phenyl ester

Chemical Property:

Purity/Quality:

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Technology Process of Phosphoric acid di-tert-butyl ester 2,4-dibromo-phenyl ester

There total 1 articles about Phosphoric acid di-tert-butyl ester 2,4-dibromo-phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

phosphorus oxychloride di-tert-butyl ester (56119-60-9) + 2,4-dibromophenol (615-58-7) → Phosphoric acid di-tert-butyl ester 2,4-dibromo-phenyl ester (137360-74-8)

Guidance literature:

With sodium hydride; Yield given. Multistep reaction; 1) THF, 0 deg C, 5 min, 2) THF, 0 deg C, 72 h;

DOI:10.1055/s-1991-26546

Reference yield: 53.0%

Phosphoric acid di-tert-butyl ester 2,4-dibromo-phenyl ester (137360-74-8) → di-tert-butyl 5-bromo-2-hydroxyphenylphosphonate (137360-77-1)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.333333h;

DOI:10.1055/s-1991-26546

upstream raw materials:

phosphorus oxychloride di-tert-butyl ester

2,4-dibromophenol

Downstream raw materials:

di-tert-butyl 5-bromo-2-hydroxyphenylphosphonate