Bis(3,5-dimethyl-4-methoxyphenyl)chlorophosphine

Base Information

Chemical Name:Bis(3,5-dimethyl-4-methoxyphenyl)chlorophosphine
CAS No.:136802-85-2
Molecular Formula:C18H22 Cl O2 P
Molecular Weight:336.798
Hs Code.:
European Community (EC) Number:622-855-4
DSSTox Substance ID:DTXSID50402474
Nikkaji Number:J1.579.802E
Wikidata:Q82205888
Mol file:136802-85-2.mol

Synonyms:BIS(3,5-DIMETHYL-4-METHOXYPHENYL)CHLOROPHOSPHINE;136802-85-2;chloro-bis(4-methoxy-3,5-dimethylphenyl)phosphane;chlorobis(4-methoxy-3,5-dimethylphenyl)phosphine;Phosphinous chloride, P,P-bis(4-methoxy-3,5-dimethylphenyl)-;Ethyl2,2-difluoroacetoacetate;SCHEMBL459763;DTXSID50402474;JWCZKGYRAINWJA-UHFFFAOYSA-N;MFCD01630810;AKOS015910269;CS-0106835;FT-0770222;Chlorobis(3,5-dimethyl-4-methoxyphenyl)phosphine;J-006913;Bis(3,5-dimethyl-4-methoxyphenyl)chlorophosphine, 95%

Suppliers and Price of Bis(3,5-dimethyl-4-methoxyphenyl)chlorophosphine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Strem Chemicals
Bis(3,5-dimethyl-4-methoxyphenyl)chlorophosphine, min. 98%
2g
$ 194.00

Strem Chemicals
Bis(3,5-dimethyl-4-methoxyphenyl)chlorophosphine, min. 98%
500mg
$ 65.00

Sigma-Aldrich
Bis(3,5-dimethyl-4-methoxyphenyl)chlorophosphine
500mg
$ 253.00

Sigma-Aldrich
Bis(3,5-dimethyl-4-methoxyphenyl)chlorophosphine 95%
1g
$ 122.00

Sigma-Aldrich
Bis(3,5-dimethyl-4-methoxyphenyl)chlorophosphine
100mg
$ 66.00

American Custom Chemicals Corporation
BIS(3,5-DIMETHYL-4-METHOXYPHENYL)CHLOROPHOSPHINE 95.00%
500MG
$ 805.88

American Custom Chemicals Corporation
BIS(3,5-DIMETHYL-4-METHOXYPHENYL)CHLOROPHOSPHINE 95.00%
100MG
$ 622.50

Total 19 raw suppliers

Chemical Property of Bis(3,5-dimethyl-4-methoxyphenyl)chlorophosphine

Chemical Property:

Vapor Pressure:6.37E-08mmHg at 25°C
Refractive Index:n20/D1.597
Boiling Point:451.7°C at 760 mmHg
Flash Point:227°C
PSA：32.05000
Density:1.141 g/cm 3 at 25 °C
LogP:4.52390
Sensitive.:Moisture Sensitive
XLogP3:5.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:336.1045946
Heavy Atom Count:22
Complexity:298

Purity/Quality:

97% ^*data from raw suppliers

Bis(3,5-dimethyl-4-methoxyphenyl)chlorophosphine, min. 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s): C
Hazard Codes:C
Statements: 34
Safety Statements: 26-36/37/39-43-45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=CC(=C1OC)C)P(C2=CC(=C(C(=C2)C)OC)C)Cl
Uses Reactant for:Asymmetric organocatalytic electrophilic phosphinationAsymmetric hydroformulation using Taddol-based chiral phosphine-phosphite ligandsSynthesis of ferrocene-based chiral diphosphinesAlcoholysis of phosphane-boranesAsymmetric hydrogenations of bifep-type biferrocenes

Technology Process of Bis(3,5-dimethyl-4-methoxyphenyl)chlorophosphine

There total 4 articles about Bis(3,5-dimethyl-4-methoxyphenyl)chlorophosphine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (Et₂ N)PCl₂

: 14804-38-7
5-bromo-2-methoxy-1,3-dimethylbenzene

: 136802-85-2
bis(3,5-dimethyl-4-methoxy-phenyl)chlorophosphine

Guidance literature:: With magnesium; In tetrahydrofuran; pentane;

Reference yield:

: 14804-38-7
5-bromo-2-methoxy-1,3-dimethylbenzene

: 136802-85-2
bis(3,5-dimethyl-4-methoxy-phenyl)chlorophosphine

Guidance literature:: 5-bromo-2-methoxy-1,3-dimethylbenzene; With magnesium; In tetrahydrofuran; at 20 ℃; for 2h;

With diethylphosphoramidous dichloride; In tetrahydrofuran; at 0 - 50 ℃; for 3h;

With hydrogenchloride; In pentane; at 0 ℃; for 1h;
DOI:10.1016/S0957-4166(99)00341-9