(E)-methyl 5-(2-(3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-ylthio)phenoxy)pentanoate

Base Information

Chemical Name:(E)-methyl 5-(2-(3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-ylthio)phenoxy)pentanoate
CAS No.:1133966-05-8
Molecular Formula:C₂₆H₂₅N₃O₃S
Molecular Weight:459.569
Hs Code.:

Synonyms:(E)-methyl 5-(2-(3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-ylthio)phenoxy)pentanoate

Suppliers and Price of (E)-methyl 5-(2-(3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-ylthio)phenoxy)pentanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (E)-methyl 5-(2-(3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-ylthio)phenoxy)pentanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (E)-methyl 5-(2-(3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-ylthio)phenoxy)pentanoate

There total 10 articles about (E)-methyl 5-(2-(3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-ylthio)phenoxy)pentanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

: 1133966-04-7
(E)-methyl 5-(2-(3-(2-(pyridin-2-yl)vinyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-ylthio)phenoxy)pentanoate

: 1133966-05-8
(E)-methyl 5-(2-(3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-ylthio)phenoxy)pentanoate

Guidance literature:: With toluene-4-sulfonic acid; In methanol; ethanol; water; at 65 ℃;

Reference yield:

: 886230-75-7
(Ε)-6-nitro-3-[2-(pyridin-2-yl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)indazole

: 1133966-05-8
(E)-methyl 5-(2-(3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-ylthio)phenoxy)pentanoate

Guidance literature:: Multi-step reaction with 4 steps

1.1: ammonium chloride; iron / ethanol; water / 2 h / 50 °C

2.1: hydrogenchloride; sodium nitrite; acetic acid / water / 0 °C

2.2: 2 h / 0 °C

3.1: caesium carbonate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / dichloromethane; N,N-dimethyl-formamide / 16 h / 80 °C

4.1: toluene-4-sulfonic acid / ethanol; water; methanol / 65 °C

With hydrogenchloride; iron; ammonium chloride; caesium carbonate; toluene-4-sulfonic acid; acetic acid; sodium nitrite; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In methanol; ethanol; dichloromethane; water; N,N-dimethyl-formamide;

Reference yield:

: 1121-24-0
ortho-mercaptophenol

: 1133966-05-8
(E)-methyl 5-(2-(3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-ylthio)phenoxy)pentanoate

Guidance literature:: Multi-step reaction with 5 steps

1: iodine / water; methanol

2: potassium carbonate / N,N-dimethyl-formamide / 12 h / 70 °C

3: zinc; acetic acid / 3 h / 116 °C / Reflux

4: caesium carbonate / (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / dichloromethane; N,N-dimethyl-formamide / 16 h / 80 °C

5: toluene-4-sulfonic acid / ethanol; water; methanol / 65 °C

With iodine; potassium carbonate; caesium carbonate; toluene-4-sulfonic acid; acetic acid; zinc; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In methanol; ethanol; dichloromethane; water; N,N-dimethyl-formamide;