Z-FA-fluoromethyl ketone

Base Information

Chemical Name:Z-FA-fluoromethyl ketone
CAS No.:105637-38-5
Molecular Formula:C₂₁H₂₃FN₂O₄
Molecular Weight:386.423
Hs Code.:
UNII:1Q2Z3U96CG
Nikkaji Number:J549.969K
Wikipedia:Z-FA-FMK
Pharos Ligand ID:C63L23RUR6B4
ChEMBL ID:CHEMBL2402203
Mol file:105637-38-5.mol

Synonyms:benzyloxycarbonyl-Phe-Ala-fluormethylketone;benzyloxycarbonylphenylalanyl-alanine fluoromethyl ketone;carbobenzoxy-L-phenylalanyl-(D,L)-alanyl fluoromethyl ketone;MDL 201053;MDL 201053, (R-(R*,S*))-isomer;MDL 201053, (S-(R*,R*))-isomer;MDL 201117;MDL-201053;MDL-201117;Z-FA-FMK;Z-Phe-Ala-CH2F;Z-Phe-Ala-FMK;Z-Phe-AlaCH2F;ZFA-fmk

Suppliers and Price of Z-FA-fluoromethyl ketone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
Caspase Inhibitor, Negative Control
5mg
$ 469.00

Sigma-Aldrich
Z-Phe-Ala fluoromethyl ketone ≥90% (TLC), powder
3mg
$ 224.00

Biorbyt Ltd
Z-FA-FMK >99%
250 mg
$ 3580.20

Biorbyt Ltd
Z-FA-FMK >99%
100 mg
$ 1949.90

Biorbyt Ltd
Z-FA-FMK >99%
50 mg
$ 1133.90

ApexBio Technology
Z-FA-FMK
1mg
$ 60.00

ApexBio Technology
Z-FA-FMK
1unit
$ 28.00

ApexBio Technology
Z-FA-FMK
5mg
$ 200.00

ApexBio Technology
Z-FA-FMK
25mg
$ 400.00

ApexBio Technology
Z-FA-FMK
10mg
$ 360.00

Total 18 raw suppliers

Chemical Property of Z-FA-fluoromethyl ketone

Chemical Property:

Appearance/Colour:powder, white to off-white
Boiling Point:630.5±55.0 °C(Predicted)
PKA:11.07±0.46(Predicted)
PSA：84.50000
Density:1 +-.0.06 g/cm3(Predicted)
LogP:3.34920
Storage Temp.:−20°C
Solubility.:DMSO or DMF: 20 mM
XLogP3:3.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:10
Exact Mass:386.16418538
Heavy Atom Count:28
Complexity:517

Purity/Quality:

97% ^*data from raw suppliers

Caspase Inhibitor, Negative Control ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(=O)CF)NC(=O)C(CC1=CC=CC=C1)NC(=O)OCC2=CC=CC=C2
Isomeric SMILES:C[C@@H](C(=O)CF)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)OCC2=CC=CC=C2
Uses Cell permeable negative control for FMK-labelled caspase inhibitors. Also an irreversible inhibitor of cathepsins B, L, and S Z-FA-FMK is an irreversible cysteine protease inhibitor. It also inhibits papain and cruzain.

Technology Process of Z-FA-fluoromethyl ketone

There total 1 articles about Z-FA-fluoromethyl ketone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: