(S)-4-(2-(2-(3-(N-(tert-butoxycarbonyl)-methylsulfonamido)-4-methoxybenzoyloxy)acetoxy)-2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)ethyl)-3,5-dichloropyridine 1-oxide

Base Information

Chemical Name:(S)-4-(2-(2-(3-(N-(tert-butoxycarbonyl)-methylsulfonamido)-4-methoxybenzoyloxy)acetoxy)-2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)ethyl)-3,5-dichloropyridine 1-oxide
CAS No.:1428847-55-5
Molecular Formula:C₃₄H₃₆Cl₂F₂N₂O₁₂S
Molecular Weight:805.635
Hs Code.:

(S)-4-(2-(2-(3-(N-(tert-butoxycarbonyl)-methylsulfonamido)-4-methoxybenzoyloxy)acetoxy)-2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)ethyl)-3,5-dichloropyridine 1-oxide

Synonyms:(S)-4-(2-(2-(3-(N-(tert-butoxycarbonyl)-methylsulfonamido)-4-methoxybenzoyloxy)acetoxy)-2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)ethyl)-3,5-dichloropyridine 1-oxide

Suppliers and Price of (S)-4-(2-(2-(3-(N-(tert-butoxycarbonyl)-methylsulfonamido)-4-methoxybenzoyloxy)acetoxy)-2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)ethyl)-3,5-dichloropyridine 1-oxide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-4-(2-(2-(3-(N-(tert-butoxycarbonyl)-methylsulfonamido)-4-methoxybenzoyloxy)acetoxy)-2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)ethyl)-3,5-dichloropyridine 1-oxide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-4-(2-(2-(3-(N-(tert-butoxycarbonyl)-methylsulfonamido)-4-methoxybenzoyloxy)acetoxy)-2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)ethyl)-3,5-dichloropyridine 1-oxide

There total 7 articles about (S)-4-(2-(2-(3-(N-(tert-butoxycarbonyl)-methylsulfonamido)-4-methoxybenzoyloxy)acetoxy)-2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)ethyl)-3,5-dichloropyridine 1-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: (S)-3,5-dichloro-4-(2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)-2-hydroxyethyl)pyridine 1-oxide

: 1428847-54-4
2-(3-(N-(tert-butoxycarbonyl)methylsulfonamido)-4-methoxybenzoyloxy)acetic acid?

: 1428847-55-5
(S)-4-(2-(2-(3-(N-(tert-butoxycarbonyl)-methylsulfonamido)-4-methoxybenzoyloxy)acetoxy)-2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)ethyl)-3,5-dichloropyridine 1-oxide

Guidance literature:: With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 2h;

Reference yield:

: 24812-90-6
methyl 3-amino-4-methoxybenzoate

: 1428847-55-5
(S)-4-(2-(2-(3-(N-(tert-butoxycarbonyl)-methylsulfonamido)-4-methoxybenzoyloxy)acetoxy)-2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)ethyl)-3,5-dichloropyridine 1-oxide

Guidance literature:: Multi-step reaction with 6 steps

1: pyridine / 2 h / 20 °C

2: dmap / dichloromethane / 2 h / 20 °C

3: tin(II) chloride dihdyrate; lithium hydroxide / tetrahydrofuran / 24 h / 20 °C

4: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 1 h / 20 °C

5: palladium 10% on activated carbon; hydrogen / methanol; ethyl acetate / 3 h / 1034.32 Torr

6: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 2 h / 20 °C

With pyridine; dmap; tin(II) chloride dihdyrate; palladium 10% on activated carbon; hydrogen; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; lithium hydroxide; In tetrahydrofuran; methanol; dichloromethane; ethyl acetate;

Reference yield:

: 29655-68-3
methyl 4-methoxy-3-(methylsulfonamido)benzoate

: 1428847-55-5
(S)-4-(2-(2-(3-(N-(tert-butoxycarbonyl)-methylsulfonamido)-4-methoxybenzoyloxy)acetoxy)-2-(3-(cyclopropylmethoxy)-4-(difluoromethoxy)phenyl)ethyl)-3,5-dichloropyridine 1-oxide

Guidance literature:: Multi-step reaction with 5 steps

1: dmap / dichloromethane / 2 h / 20 °C

2: tin(II) chloride dihdyrate; lithium hydroxide / tetrahydrofuran / 24 h / 20 °C

3: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 1 h / 20 °C

4: palladium 10% on activated carbon; hydrogen / methanol; ethyl acetate / 3 h / 1034.32 Torr

5: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 2 h / 20 °C

With dmap; tin(II) chloride dihdyrate; palladium 10% on activated carbon; hydrogen; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; lithium hydroxide; In tetrahydrofuran; methanol; dichloromethane; ethyl acetate;