(E)-5-bromo-N'-(1-(4,5-difluoro-1H-indol-2-yl)ethylidene)-2-hydroxybenzohydrazide

Base Information

Chemical Name:(E)-5-bromo-N'-(1-(4,5-difluoro-1H-indol-2-yl)ethylidene)-2-hydroxybenzohydrazide
CAS No.:1373438-14-2
Molecular Formula:C₁₇H₁₂BrF₂N₃O₂
Molecular Weight:408.202
Hs Code.:

Synonyms:(E)-5-bromo-N'-(1-(4,5-difluoro-1H-indol-2-yl)ethylidene)-2-hydroxybenzohydrazide

Suppliers and Price of (E)-5-bromo-N'-(1-(4,5-difluoro-1H-indol-2-yl)ethylidene)-2-hydroxybenzohydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (E)-5-bromo-N'-(1-(4,5-difluoro-1H-indol-2-yl)ethylidene)-2-hydroxybenzohydrazide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (E)-5-bromo-N'-(1-(4,5-difluoro-1H-indol-2-yl)ethylidene)-2-hydroxybenzohydrazide

There total 4 articles about (E)-5-bromo-N'-(1-(4,5-difluoro-1H-indol-2-yl)ethylidene)-2-hydroxybenzohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 1373438-99-3
1-(4,5-difluoro-1H-indol-2-yl)ethanone

: 39635-10-4
2-hydroxy-5-bromobenzohydrazide

: 1373438-14-2
(E)-5-bromo-N'-(1-(4,5-difluoro-1H-indol-2-yl)ethylidene)-2-hydroxybenzohydrazide

Guidance literature:: In propan-1-ol; Reflux;
DOI:10.1016/j.bmc.2012.10.002

Reference yield: 75.0%

: 1373438-14-2
(E)-5-bromo-N'-(1-(4,5-difluoro-1H-indol-2-yl)ethylidene)-2-hydroxybenzohydrazide

Guidance literature:

Reference yield:

: 161958-41-4
3,4-difluoro-2-iodoaniline

: 1373438-14-2
(E)-5-bromo-N'-(1-(4,5-difluoro-1H-indol-2-yl)ethylidene)-2-hydroxybenzohydrazide

Guidance literature:: Multi-step reaction with 3 steps

1: 1,4-diaza-bicyclo[2.2.2]octane; palladium diacetate / N,N-dimethyl-formamide / 16 h / 105 °C

2: diethyl ether / 2 h / 0 °C / Reflux

3: propan-1-ol / Reflux

With 1,4-diaza-bicyclo[2.2.2]octane; palladium diacetate; In propan-1-ol; diethyl ether; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2012.10.002