N-Boc-3-aminophenylacetic Acid

Base Information

Chemical Name:N-Boc-3-aminophenylacetic Acid
CAS No.:123036-51-1
Molecular Formula:C13H17NO4
Molecular Weight:251.282
Hs Code.:29225090
European Community (EC) Number:674-318-9
DSSTox Substance ID:DTXSID80375440
Wikidata:Q82163974
Mol file:123036-51-1.mol

Synonyms:N-Boc-3-aminophenylacetic Acid;123036-51-1;3-tert-Butoxy carbonylaminophenyl acetic acid;2-[3-[(2-methylpropan-2-yl)oxycarbonylamino]phenyl]acetic Acid;3-aminophenylacetic acid, n-boc protected;Benzeneacetic acid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-;MFCD02682313;boc-3-aminophenylacetic acid;N-Boc-3-aminophenylaceticAcid;3-(Boc-amino)phenylacetic acid;2-(3-((tert-butoxycarbonyl)amino)phenyl)acetic acid;Benzeneacetic acid,3-[[(1,1-dimethylethoxy)carbonyl]amino]-;SCHEMBL999345;DTXSID80375440;AKOS009159324;AC-7205;SY005118;FT-0677329;EN300-88658;3-[(tert-Butoxycarbonyl)amino]phenylacetic acid;2-(3-(tert-butoxycarbonylamino)phenyl)acetic acid;A890862;2-(3-{[(tert-butoxy)carbonyl]amino}phenyl)acetic acid;{3-[(tert-Butoxycarbonyl)amino]phenyl}acetic acid, AldrichCPR

Suppliers and Price of N-Boc-3-aminophenylacetic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-Boc-3-AminophenylaceticAcid
500mg
$ 155.00

SynQuest Laboratories
3-[(tert-Butoxycarbonyl)amino]phenylacetic acid
25 g
$ 1328.00

SynQuest Laboratories
3-[(tert-Butoxycarbonyl)amino]phenylacetic acid
1 g
$ 125.00

SynQuest Laboratories
3-[(tert-Butoxycarbonyl)amino]phenylacetic acid
5 g
$ 360.00

Matrix Scientific
3-tert-Butoxy carbonylaminophenyl acetic acid 98%
5g
$ 310.00

Matrix Scientific
3-tert-Butoxy carbonylaminophenyl acetic acid 98%
500mg
$ 63.00

Matrix Scientific
3-tert-Butoxy carbonylaminophenyl acetic acid 98%
1g
$ 97.00

Crysdot
N-Boc-3-Aminophenylaceticacid 98%
1g
$ 111.00

Biosynth Carbosynth
Boc-3-aminophenylacetic acid
1 g
$ 279.00

Biosynth Carbosynth
Boc-3-aminophenylacetic acid
2 g
$ 446.40

Total 19 raw suppliers

Chemical Property of N-Boc-3-aminophenylacetic Acid

Chemical Property:

Vapor Pressure:1.13E-05mmHg at 25°C
Melting Point:100-102 °C
Refractive Index:1.566
Boiling Point:355.6 °C at 760 mmHg
Flash Point:168.9 °C
PSA：75.63000
Density:1.22 g/cm³
LogP:2.73370
Storage Temp.:2-8°C
XLogP3:1.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:251.11575802
Heavy Atom Count:18
Complexity:309

Purity/Quality:

97% ^*data from raw suppliers

N-Boc-3-AminophenylaceticAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC1=CC=CC(=C1)CC(=O)O

Technology Process of N-Boc-3-aminophenylacetic Acid

There total 4 articles about N-Boc-3-aminophenylacetic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.8%

: 24424-99-5
di-tert-butyl dicarbonate

: 14338-36-4
3-amino phenylacetic acid

: 123036-51-1
2-(3-((tert-butoxycarbonyl)amino)phenyl)acetic acid

Guidance literature:: With sodium hydroxide; In 1,4-dioxane; water; at 20 ℃; for 6h;
DOI:10.1016/S0040-4020(02)01093-1

Reference yield:

: 2-(3-((tert-butoxycarbonyl)amino)phenyl)ethanoic acid methyl ester

: 123036-51-1
2-(3-((tert-butoxycarbonyl)amino)phenyl)acetic acid

Guidance literature:: With water; sodium hydroxide; In methanol; at 20 ℃; for 2h;

Reference yield:

: 1878-67-7
3-Bromophenylacetic acid

: 123036-51-1
2-(3-((tert-butoxycarbonyl)amino)phenyl)acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: sulfuric acid / 3 h / 60 °C

2: tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; caesium carbonate / 1,4-dioxane / 5 h / 100 °C / Inert atmosphere

3: sodium hydroxide; water / methanol / 2 h / 20 °C

With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; sulfuric acid; water; caesium carbonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; sodium hydroxide; In 1,4-dioxane; methanol;