2,3-Dihydro-1-benzofuran-7-carbonyl chloride

Base Information

• Chemical Name: 2,3-Dihydro-1-benzofuran-7-carbonyl chloride
• CAS No.: 123266-63-7
• Molecular Formula: C₉H₇ClO₂
• Molecular Weight: 182.606
• Hs Code.: 2932990090
• DSSTox Substance ID: DTXSID70383519
• Wikidata: Q82175278
• Mol file: 123266-63-7.mol

Synonyms:123266-63-7;2,3-dihydro-1-benzofuran-7-carbonyl chloride;2,3-Dihydrobenzo[b]furan-7-carbonyl chloride;2,3-dihydrobenzofuran-7-carbonyl chloride;7-Benzofurancarbonyl chloride, 2,3-dihydro-;2,3-DIHYDRO-1-BENZOFURAN-7-CARBONYLCHLORIDE;7-Benzofurancarbonylchloride, 2,3-dihydro-;SCHEMBL1021074;DTXSID70383519;KNBGUBMIJPZGHF-UHFFFAOYSA-N;MFCD06658967;AKOS006345238;2,3-dihydrobenzo[b]furan-7-oyl chloride;2-(2-N-BOC-PYRROLE)PHENYLACETICACID;FT-0721776;2,3-dihydro-1-benzo[b]furan-7-carbonyl chloride;J-507016

Chemical Property of 2,3-Dihydro-1-benzofuran-7-carbonyl chloride

Chemical Property:

• Vapor Pressure: 0.00116mmHg at 25°C
• Refractive Index: 1.586
• Boiling Point: 299.8 °C at 760 mmHg
• Flash Point: 111.6 °C
• PSA: 26.30000
• Density: 1.342 g/cm³
• LogP: 2.00050
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 182.0134572
• Heavy Atom Count: 12
• Complexity: 193

Purity/Quality:

98%min ^*data from raw suppliers

2,3-Dihydrobenzo[b]furan-7-carbonylchloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1COC2=C1C=CC=C2C(=O)Cl

Technology Process of 2,3-Dihydro-1-benzofuran-7-carbonyl chloride

There total 9 articles about 2,3-Dihydro-1-benzofuran-7-carbonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

→ 2,3-Dihydro-7-benzofurancarboxylic acid chloride (123266-63-7)

Guidance literature:

Reference yield:

2,3-dihydrobenzofuran-7-carboxylic acid (35700-40-4) → 2,3-Dihydro-7-benzofurancarboxylic acid chloride (123266-63-7)

Guidance literature:

With thionyl chloride; N,N-dimethyl-formamide; In chloroform; for 2h; Heating;

DOI:10.1021/jm00163a029

Reference yield:

oxalyl dichloride (79-37-8) + 2,3-dihydrobenzofuran-7-carboxylic acid (35700-40-4) → 2,3-Dihydro-7-benzofurancarboxylic acid chloride (123266-63-7)

Guidance literature:

In N-methyl-acetamide; dichloromethane;

upstream raw materials:

2,3-dihydrobenzofuran-7-carboxylic acid

2.3-dihydrobenzofuran

2-vinyloxy-benzoic acid methyl ester

2,3-dihydro-benzofuran-7-carboxylic acid methyl ester

Downstream raw materials:

2,3-dihydro-benzofuran-7-carboxylic acid methyl ester

2,3-Dihydro-N-<4-(1,1-dimethylethyl)phenylmethyl>-N-methyl-7-benzofurancarboxamid

7-benzofuranylcarboxylic acid

methyl benzofuran-7-carboxylate