(1R,2R)-3-(3-dimethylamino-1-ethyl-2-methylpropyl)phenol nitrate

Base Information

• Chemical Name: (1R,2R)-3-(3-dimethylamino-1-ethyl-2-methylpropyl)phenol nitrate
• CAS No.: 1356394-24-5
• Molecular Formula: C₁₄H₂₃NO*HNO₃
• Molecular Weight: 284.356
• Mol file: 1356394-24-5.mol

Synonyms:(1R,2R)-3-(3-dimethylamino-1-ethyl-2-methylpropyl)phenol nitrate

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Chemical Property of (1R,2R)-3-(3-dimethylamino-1-ethyl-2-methylpropyl)phenol nitrate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1R,2R)-3-(3-dimethylamino-1-ethyl-2-methylpropyl)phenol nitrate

There total 2 articles about (1R,2R)-3-(3-dimethylamino-1-ethyl-2-methylpropyl)phenol nitrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

tapentadol (175591-23-8) → (1R,2R)-3-(3-dimethylamino-1-ethyl-2-methylpropyl)phenol nitrate (1356394-24-5)

Guidance literature:

With nitric acid; In acetone; at 20 ℃; for 16h;

Reference yield: 83.0%

tapentadol (175591-23-8) + nitric acid (7697-37-2,78989-43-2) → (1R,2R)-3-(3-dimethylamino-1-ethyl-2-methylpropyl)phenol nitrate (1356394-24-5)

Guidance literature:

In acetone; at 20 ℃; for 16h;

upstream raw materials:

tapentadol

nitric acid

Refernces

• 1、 -. "SALTS OR CO-CRYSTALS OF 3-(3-DIMETHYLAMINO-1-ETHYL-2-METHYL-PROPYL)-PHENOL". Page/Page column 38. . Retrieved 2012/02/05.