1,2-di-[2-(tetradecylthio)acetyl]-sn-glycero-3-phosphocholine

Base Information

• Chemical Name: 1,2-di-[2-(tetradecylthio)acetyl]-sn-glycero-3-phosphocholine
• CAS No.: 636589-28-1
• Molecular Formula: C₄₀H₈₀NO₈PS₂
• Molecular Weight: 798.183
• Mol file: 636589-28-1.mol

Synonyms:1,2-di-[2-(tetradecylthio)acetyl]-sn-glycero-3-phosphocholine

Chemical Property of 1,2-di-[2-(tetradecylthio)acetyl]-sn-glycero-3-phosphocholine

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 1,2-di-[2-(tetradecylthio)acetyl]-sn-glycero-3-phosphocholine

There total 2 articles about 1,2-di-[2-(tetradecylthio)acetyl]-sn-glycero-3-phosphocholine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

tetradecylthioacetic Acid (2921-20-2) + L-glycero-3-phosphorylcholine (28319-77-9,563-24-6) → 1,2-di-[2-(tetradecylthio)acetyl]-sn-glycero-3-phosphocholine (636589-28-1)

Guidance literature:

tetradecylthioacetic Acid; With 1,1'-carbonyldiimidazole; In dichloromethane; at 20 ℃; for 2.75h; Inert atmosphere;

L-glycero-3-phosphorylcholine; With 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; dimethyl sulfoxide; at 20 ℃; for 16h; Inert atmosphere;

DOI:10.1021/jm801019s

Reference yield: 50.0%

tetradecylthioacetic Acid (2921-20-2) + L-glycero-3-phosphorylcholine (28319-77-9,563-24-6) → 1,2-di-[2-(tetradecylthio)acetyl]-sn-glycero-3-phosphocholine (636589-28-1) + lyso tetradecylthioacetyl-L-α-phosphatidylcholine (1218782-08-1)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide; at 20 ℃; for 16h; Inert atmosphere;

DOI:10.1016/j.bmc.2016.01.045

upstream raw materials:

tetradecylthioacetic Acid

L-glycero-3-phosphorylcholine