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2921-20-2

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2921-20-2 Usage

Description

Tetradecylthioacetic acid (TTA), a representative member of the 3-thia family, has the chemical structure of palmitic acid (C16) in which a sulfur atom is located between the 2 and 3-carbon atoms (COOH-CH2-S-(CH2)13-CH3). TTA is a novel hypolipidemic drug which has been shown to combine several effects of w-3 PUFAs, such as EPA, and structurally unrelated peroxisome proliferators, such as phenylacetate and fibrates. From this perspective we wanted to investigate if TTA shares the antitumor activity found for these functionally related compounds, and furthermore to study the metabolic effects of TTA in cancer cells in relation to the effects found in hepatocytes.

Chemical Properties

White Cyrstalline Solid

Uses

Different sources of media describe the Uses of 2921-20-2 differently. You can refer to the following data:
1. TTA is a novel thio-fatty acid which cannot undergo beta-oxidation. It induces apoptosis in IPC-81 leukemia cells via depolarization of mitochondrial membrane potential and inhibits glioma cell proliferation. TTA completely prevents high fat diet-induce
2. TTA is a novel thio-fatty acid which cannot undergo beta-oxidation. It induces apoptosis in IPC-81 leukemia cells via depolarization of mitochondrial membrane potential and inhibits glioma cell proliferation. TTA completely prevents high fat diet-induced insulin resistance and adiposity in Wistar rats. Activates rodent PPAR’s with rank order PPARα>PPARδ>PPARγ.

Check Digit Verification of cas no

The CAS Registry Mumber 2921-20-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,9,2 and 1 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 2921-20:
(6*2)+(5*9)+(4*2)+(3*1)+(2*2)+(1*0)=72
72 % 10 = 2
So 2921-20-2 is a valid CAS Registry Number.
InChI:InChI=1/C16H32O2S/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-19-15-16(17)18/h2-15H2,1H3,(H,17,18)

2921-20-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name Tetradecylthioacetic Acid

1.2 Other means of identification

Product number -
Other names Tetradecylthioacetic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2921-20-2 SDS

2921-20-2Relevant articles and documents

Metal extracting agent containing sulfoxide group and preparation method thereof

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Paragraph 0050; 0051; 0052, (2017/07/04)

The invention discloses a metal extracting agent containing a sulfoxide group and a preparation method thereof. The metal extracting agent containing the sulfoxide group is 2-(alkylsulfinyl)-N-((tetrahydrofuran-2-yl)methyl)acetamide. According to the preparation method, thioalcohol is used as a raw material, reacts with chloroacetic acid in an alkaline condition to generate corresponding thioether; afterwards, the corresponding thioether is oxidized through hydrogen peroxide in an organic-acid environment to obtain sulfoxide; the sulfoxide reacts with 2-tetrahydrofurfuryl amine in highly-acidic and high-temperature conditions, so as to generate corresponding amide. The metal extracting agent containing the sulfoxide group, which is provided by the invention, is high in the safety to an environment and an organism, is low-toxicity, is good in wettability, high in foaming capacity and liable in biodegradation, and has quite good extraction effects on rare earth metals thulium, ytterbium and lutetium in a weakly acidic condition.

NATURAL LIPIDS CONTAINING NON-OXIDIZABLE FATTY ACIDS

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Paragraph 00324-00328, (2016/02/18)

Provided herein is technology relating to natural lipids containing non-β-oxidizable fatty acids and particularly, but not exclusively, to compositions and methods related to the production and use of natural lipids containing non-β-oxidizable fatty acids.

Synthesis and characterization of some novel higher C,N-diphenyl nitrones, isoxazolines, and mercaptobenzimidazoles as oleochemicals

Yldrm,Cetin

experimental part, p. 952 - 964 (2012/08/07)

Some novel long-chain nitrones, isoxazolines, and (1H-benzo[d]-imidazol-2- ylthio) derivatives were synthesized. Nitrones, N-{4-[2-(tetradecylthio)acetoxy] benzylidene}aniline oxide, and N-[4-(12-oxo-2,5,8,11-tetraoxadocosan-22-yloxy) benzylidene]aniline oxide were prepared via the reaction of -phenylhydroxylamine with the corresponding aromatic aldehydes. The isoxazolines were prepared from undec-10-en-1-ol and benzonitrile-N-oxide which was generated in situ. The 1H-benzo[d]-imidazol-2-ylthio derivatives were synthesized via the replacement reaction of -bromo esters and 2-mercaptobenzimidazole.

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