3-(4-Chloro-2-fluoro-5-methylphenyl)-1-methyl-5-(trifluoromethyl)-1h-pyrazole

Base Information

Chemical Name:3-(4-Chloro-2-fluoro-5-methylphenyl)-1-methyl-5-(trifluoromethyl)-1h-pyrazole
CAS No.:142623-48-1
Molecular Formula:C₁₂H₉ClF₄N₂
Molecular Weight:292.663
Hs Code.:
European Community (EC) Number:432-020-4
DSSTox Substance ID:DTXSID001140524
Nikkaji Number:J3.120.517D

Synonyms:3-(4-chloro-2-fluoro-5-methylphenyl)-1-methyl-5-(trifluoromethyl)-1h-pyrazole;142623-48-1;3-(4-chloro-2-fluoro-5-methylphenyl)-1-methyl-5-(trifluoromethyl)pyrazole;SCHEMBL7521846;YNQXHQDFBVIEDP-UHFFFAOYSA-N;DTXSID001140524;1-Methyl-3-(2-fluoro-4-chloro-5-methylphenyl)-5-(trifluoromethyl)-1H-pyrazole;3-(4-Chloro-2-fluoro-5-methylphenyl)-1-methyl-5-(trifluoro methyl)-1H-pyrazole

Suppliers and Price of 3-(4-Chloro-2-fluoro-5-methylphenyl)-1-methyl-5-(trifluoromethyl)-1h-pyrazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-(4-Chloro-2-fluoro-5-methylphenyl)-1-methyl-5-(trifluoromethyl)-1H-pyrazole
100mg
$ 1710.00

Medical Isotopes, Inc.
3-(4-Chloro-2-fluoro-5-methylphenyl)-1-methyl-5-(trifluoromethyl)-1H-pyrazole
25 mg
$ 1080.00

Medical Isotopes, Inc.
3-(4-Chloro-2-fluoro-5-methylphenyl)-1-methyl-5-(trifluoromethyl)-1H-pyrazole
5 mg
$ 645.00

Total 2 raw suppliers

Chemical Property of 3-(4-Chloro-2-fluoro-5-methylphenyl)-1-methyl-5-(trifluoromethyl)-1h-pyrazole

Chemical Property:

Melting Point:44-48°C
XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:292.0390386
Heavy Atom Count:19
Complexity:325

Purity/Quality:

99.9% ^*data from raw suppliers

3-(4-Chloro-2-fluoro-5-methylphenyl)-1-methyl-5-(trifluoromethyl)-1H-pyrazole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC(=C(C=C1Cl)F)C2=NN(C(=C2)C(F)(F)F)C
Uses 3-(4-Chloro-2-fluoro-5-methylphenyl)-1-methyl-5-(trifluoromethyl)-1H-pyrazole is an intermediate in the synthesis of Fluazolate (F407500), the active ingredient in the preparation of agrochemicals and drugs in amorphous form.

Technology Process of 3-(4-Chloro-2-fluoro-5-methylphenyl)-1-methyl-5-(trifluoromethyl)-1h-pyrazole

There total 7 articles about 3-(4-Chloro-2-fluoro-5-methylphenyl)-1-methyl-5-(trifluoromethyl)-1h-pyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 1067233-79-7
4-trifluoromethyl-N-methylsydnone

: 200190-84-7
1-chloro-4-ethynyl-5-fluoro-2-methylbenzene

: 142623-48-1
1-(4-chloro-2-fluoro-5-methylphenyl [ring-14C(U)])-1-methyl-5-(trifluoromethyl)-1H-pyrazole

Guidance literature:: In 1,2-dichloro-benzene; at 180 ℃; for 24h; Sealed tube;
DOI:10.1021/ol3021918

Reference yield: 74.0%

: 77-78-1
dimethyl sulfate

: 142623-96-9
1-(4-chloro-2-fluoro-5-methylphenyl [ring-14C(U)])-5-(trifluoromethyl)-1H-pyrazole

: 142623-48-1
1-(4-chloro-2-fluoro-5-methylphenyl [ring-14C(U)])-1-methyl-5-(trifluoromethyl)-1H-pyrazole

Guidance literature:: In toluene; for 6h; Heating;
DOI:10.1002/1099-1344(200006)43:7<645::AID-JLCR349>3.0.CO;2-6

Reference yield:

: 1396123-92-4
1-methyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(trifluoromethyl)-1H-pyrazole

: 200190-87-0
3-bromo-6-chloro-4-fluoro-toluene

: 142623-48-1
1-(4-chloro-2-fluoro-5-methylphenyl [ring-14C(U)])-1-methyl-5-(trifluoromethyl)-1H-pyrazole

Guidance literature:: With bis-triphenylphosphine-palladium(II) chloride; potassium phosphate; In 1,4-dioxane; at 85 ℃; for 24h; Inert atmosphere;
DOI:10.1021/ol3021918