Benzeneethanol, b-amino-a,a-diphenyl-, (bR)-

Base Information

• Chemical Name: Benzeneethanol, b-amino-a,a-diphenyl-, (bR)-
• CAS No.: 79868-79-4
• Molecular Formula: C₂₀H₁₉NO
• Molecular Weight: 289.377
• Hs Code.: 2922190090
• Mol file: 79868-79-4.mol

Synonyms:Benzeneethanol,b-amino-a,a-diphenyl-, (R)-;(2R)-2-Amino-1,1,2-triphenylethanol;(R)-(+)-1,1,2-Triphenyl-2-aminoethanol;(R)-2-Amino-1,1,2-triphenylethanol;

Chemical Property of Benzeneethanol, b-amino-a,a-diphenyl-, (bR)-

Chemical Property:

• Vapor Pressure: 4.17E-09mmHg at 25°C
• Melting Point: 130-131oC
• Refractive Index: 1.637
• Boiling Point: 456 °C at 760 mmHg
• PKA: 10.89±0.50(Predicted)
• Flash Point: 229.6 °C
• PSA: 46.25000
• Density: 1.162 g/cm³
• LogP: 4.32280
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

97% ^*data from raw suppliers

(R)-2-(+)-Amino-1,1,2-triphenylethanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzeneethanol, b-amino-a,a-diphenyl-, (bR)-

There total 19 articles about Benzeneethanol, b-amino-a,a-diphenyl-, (bR)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

(R)-1-tert-butyl-N-(2-(methoxymethoxy)-1,2,2-triphenylethyl)-1-(λ1-oxidanyl)-λ3-sulfanamine → (R)-(+)-2-amino-1,1,2-triphenylethanol (60539-17-5,79868-79-4,129704-13-8)

Guidance literature:

(R)-1-tert-butyl-N-(2-(methoxymethoxy)-1,2,2-triphenylethyl)-1-(λ¹-oxidanyl)-λ³-sulfanamine; With hydrogenchloride; In methanol; at 0 - 70 ℃; for 4h;

With sodium hydrogencarbonate; In tetrahydrofuran; methanol; at 20 ℃; for 6h;

DOI:10.1021/acs.joc.8b01381

Reference yield: 91.0%

(R)-2-(allylamino)-1,1,2-triphenylethonol → (R)-(+)-2-amino-1,1,2-triphenylethanol (60539-17-5,79868-79-4,129704-13-8)

Guidance literature:

With palladium on activated charcoal; methanesulfonic acid; Heating;

DOI:10.1021/jo050960+

Reference yield: 73.0%

D-phenylglycine methyl ester hydrochloride (19883-41-1,13226-98-7) + phenylmagnesium bromide (100-58-3) → (R)-(+)-2-amino-1,1,2-triphenylethanol (60539-17-5,79868-79-4,129704-13-8)

Guidance literature:

In diethyl ether; for 7h; Ambient temperature;

DOI:10.1021/jo9612943

upstream raw materials:

benzophenone

benzylamine

hippuric acid-(2-hydroxy-1,2,2-triphenyl-ethylamide)

N-benzylidene-2-methoxy-1-phenylethanamine

Downstream raw materials:

4,5,5-triphenyl-oxazolidin-2-one

hippuric acid-(2-hydroxy-1,2,2-triphenyl-ethylamide)

benzophenone

benzylamine