(R)-4-Methyl-5,5-diphenyloxazolidin-2-one

Base Information

Chemical Name:(R)-4-Methyl-5,5-diphenyloxazolidin-2-one
CAS No.:223906-37-4
Molecular Formula:C16H15NO2
Molecular Weight:253.3
Hs Code.:29349990
DSSTox Substance ID:DTXSID70444098
Nikkaji Number:J1.092.498G
Wikidata:Q82262108
Mol file:223906-37-4.mol

Synonyms:223906-37-4;(R)-4-Methyl-5,5-diphenyloxazolidin-2-one;(R)-(+)-5,5-Diphenyl-4-methyl-2-oxazolidinone;(4R)-4-Methyl-5,5-diphenyl-1,3-oxazolidin-2-one;DTXSID70444098;AMY37520;YIA90637;AKOS016843384;A3837;(R)-4-Methyl-5,5-diphenyloxazolidine-2-one;(R)-(+)-4-Methyl-5,5-diphenyl-2-oxazolidinone;(R)-(+)-5,5-Diphenyl-4-methyl-2-oxazolidinone, 97%

Suppliers and Price of (R)-4-Methyl-5,5-diphenyloxazolidin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
(R)-(+)-5,5-Diphenyl-4-methyl-2-oxazolidinone 97%
5g
$ 559.00

Sigma-Aldrich
(R)-(+)-5,5-Diphenyl-4-methyl-2-oxazolidinone 97%
1g
$ 134.00

Crysdot
(R)-4-Methyl-5,5-diphenyloxazolidin-2-one 95+%
5g
$ 594.00

Chemenu
(R)-4-methyl-5,5-diphenyloxazolidin-2-one 95%
5g
$ 561.00

American Custom Chemicals Corporation
(R)-(+)-5,5-DIPHENYL-4-METHYL-2-OXAZOLIDINONE 97.00%
100MG
$ 132.30

Total 11 raw suppliers

Chemical Property of (R)-4-Methyl-5,5-diphenyloxazolidin-2-one

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:268-272 °C(lit.)
Refractive Index:1.575
Boiling Point:464.953 °C at 760 mmHg
Flash Point:234.995 °C
PSA：38.33000
Density:1.156 g/cm³
LogP:3.38730
XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:253.110278721
Heavy Atom Count:19
Complexity:312

Purity/Quality:

99% ^*data from raw suppliers

(R)-(+)-5,5-Diphenyl-4-methyl-2-oxazolidinone 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1C(OC(=O)N1)(C2=CC=CC=C2)C3=CC=CC=C3
Isomeric SMILES:C[C@@H]1C(OC(=O)N1)(C2=CC=CC=C2)C3=CC=CC=C3

Technology Process of (R)-4-Methyl-5,5-diphenyloxazolidin-2-one

There total 2 articles about (R)-4-Methyl-5,5-diphenyloxazolidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 223906-32-9
(2R)-N-Boc-2-amino-1,1-diphenylpropanol

: 223906-37-4
(4R)-5,5-Diphenyl-4-methyloxazolidin-2-one

Guidance literature:: With potassium tert-butylate; In tetrahydrofuran; at 0 ℃; for 0.5h;
DOI:10.1039/a809715a

Reference yield:

: 42746-51-0
5,5-diphenyl-4-methyl-2-oxazolidinone

: 191090-29-6
(S)-4-Methyl-5,5-diphenyl-oxazolidin-2-one

: 223906-37-4
(4R)-5,5-Diphenyl-4-methyloxazolidin-2-one

Guidance literature:: With trifluoroacetic acid; In hexane; isopropyl alcohol; Reagent/catalyst; Resolution of racemate;
DOI:10.1002/chir.22766

Reference yield: 80.0%

: 100-39-0
benzyl bromide

: 223906-37-4
(4R)-5,5-Diphenyl-4-methyloxazolidin-2-one

: (4R)-N-Benzyl-5,5-diphenyl-4-methyloxazolidin-2-one

Guidance literature:: With n-butyllithium; In tetrahydrofuran; 1.) -78 deg C, 15 min, 2.) -78 deg C, 30 min; -78 deg C to r.t., 24 h;
DOI:10.1039/a809715a