2-(4-hydroxymethylphenyl)-2-methylpropionic acid methyl ester

Base Information

• Chemical Name: 2-(4-hydroxymethylphenyl)-2-methylpropionic acid methyl ester
• CAS No.: 630385-57-8
• Molecular Formula: C₁₂H₁₆O₃
• Molecular Weight: 208.257
• Mol file: 630385-57-8.mol

Synonyms:2-(4-hydroxymethylphenyl)-2-methylpropionic acid methyl ester

Chemical Property of 2-(4-hydroxymethylphenyl)-2-methylpropionic acid methyl ester

Chemical Property:

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Technology Process of 2-(4-hydroxymethylphenyl)-2-methylpropionic acid methyl ester

There total 1 articles about 2-(4-hydroxymethylphenyl)-2-methylpropionic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(2-methoxy-1,1-dimethyl-2-oxoethyl)benzoic acid (630385-56-7) → 2-(4-hydroxymethylphenyl)-2-methylpropionic acid methyl ester (630385-57-8)

Guidance literature:

With borane-THF; In tetrahydrofuran; at 20 - 65 ℃; for 7h;

Reference yield:

2-(4-hydroxymethylphenyl)-2-methylpropionic acid methyl ester (630385-57-8) + Dess-Martin periodane (87413-09-0) → 2-(4-formylphenyl)-2-methylpropionic acid methyl ester (84542-11-0)

Guidance literature:

In dichloromethane; at 20 ℃; for 4h;

upstream raw materials:

4-(2-methoxy-1,1-dimethyl-2-oxoethyl)benzoic acid

Downstream raw materials:

2-(4-formylphenyl)-2-methylpropionic acid methyl ester