4-(Dodecyloxy)benzamide

Base Information

• Chemical Name: 4-(Dodecyloxy)benzamide
• CAS No.: 179341-69-6
• Molecular Formula: C19H31NO2
• Molecular Weight: 305.461
• European Community (EC) Number: 605-856-4
• DSSTox Substance ID: DTXSID10598488
• Nikkaji Number: J1.801.001A
• Wikidata: Q82494252
• Mol file: 179341-69-6.mol

Synonyms:4-n-Dodecyloxybenzamide;4-(dodecyloxy)benzamide;4-dodecoxybenzamide;179341-69-6;4-DODECYLOXYBENZAMIDE;SCHEMBL4652240;DTXSID10598488;AKOS015910960

Chemical Property of 4-(Dodecyloxy)benzamide

Chemical Property:

• Vapor Pressure: 5.38E-08mmHg at 25°C
• Refractive Index: 1.503
• Boiling Point: 441.6 °C at 760 mmHg
• Flash Point: 140.1 °C
• PSA: 52.32000
• Density: 0.973 g/cm³
• LogP: 5.78550
• XLogP3: 6.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 13
• Exact Mass: 305.235479232
• Heavy Atom Count: 22
• Complexity: 273

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCOC1=CC=C(C=C1)C(=O)N

Technology Process of 4-(Dodecyloxy)benzamide

There total 4 articles about 4-(Dodecyloxy)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

4-(dodecyloxy)benzonitrile (29147-92-0) → 4-(dodecyloxy)benzamide (179341-69-6)

Guidance literature:

With sodium percarbonate; water; In acetone; at 50 ℃; for 9h;

DOI:10.1002/chem.200801408

Reference yield: 83.5%

p-hydroxybenzamide (619-57-8) + 1-dodecylbromide (143-15-7) → 4-(dodecyloxy)benzamide (179341-69-6)

Guidance literature:

With potassium carbonate; potassium iodide; In acetone; for 48h; Reflux;

DOI:10.1039/c9ra08211e

Reference yield: 70.0%

4-n-dodecyloxybenzaldehyde (24083-19-0) → 4-(dodecyloxy)benzamide (179341-69-6)

Guidance literature:

4-n-dodecyloxybenzaldehyde; With 9-aminofluorene; In toluene; at 20 ℃; for 0.5h;

With oxygen; triethylamine; In toluene; for 1.5h; Reflux;

DOI:10.1021/acs.orglett.6b02465

upstream raw materials:

1-Iodododecane

4-cyanophenol

4-(dodecyloxy)benzonitrile

4-n-dodecyloxybenzaldehyde

Downstream raw materials:

4-(dodecyloxy)aniline