Ethyl 1-acetylcyclobutane-1-carboxylate

Base Information

Chemical Name:Ethyl 1-acetylcyclobutane-1-carboxylate
CAS No.:126290-87-7
Molecular Formula:C₉H₁₄O₃
Molecular Weight:170.208
Hs Code.:2902900000
European Community (EC) Number:696-340-8
DSSTox Substance ID:DTXSID00477834
Wikidata:Q82310812
Mol file:126290-87-7.mol

Synonyms:ethyl 1-acetylcyclobutane-1-carboxylate;126290-87-7;Ethyl 1-acetylcyclobutanecarboxylate;C9H14O3;SCHEMBL5787834;DTXSID00477834;Ethyl1-acetylcyclobutanecarboxylate;RMXJKLCXYPHSMA-UHFFFAOYSA-N;BFA29087;AKOS016028526;GG-0714;CS-0361347

Suppliers and Price of Ethyl 1-acetylcyclobutane-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
Ethyl 1-acetylcyclobutane-1-carboxylate >95%
500mg
$ 262.00

Matrix Scientific
Ethyl 1-acetylcyclobutane-1-carboxylate >95%
1g
$ 328.00

Crysdot
Ethyl1-acetylcyclobutanecarboxylate 95+%
1g
$ 325.00

American Custom Chemicals Corporation
ETHYL-1-ACETYLCYCLOBUTANE-1-CARBOXYLATE 95.00%
5MG
$ 496.91

AK Scientific
Ethyl1-acetylcyclobutane-1-carboxylate
5g
$ 1667.00

AK Scientific
Ethyl1-acetylcyclobutane-1-carboxylate
1g
$ 473.00

Total 10 raw suppliers

Chemical Property of Ethyl 1-acetylcyclobutane-1-carboxylate

Chemical Property:

XLogP3:1.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:170.094294304
Heavy Atom Count:12
Complexity:204

Purity/Quality:

99% ^*data from raw suppliers

Ethyl 1-acetylcyclobutane-1-carboxylate >95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1(CCC1)C(=O)C

Technology Process of Ethyl 1-acetylcyclobutane-1-carboxylate

There total 6 articles about Ethyl 1-acetylcyclobutane-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

: 141-97-9
ethyl acetoacetate

: 109-64-8
1,3-dibromo-propane

: 503-30-0
trimethylene oxide

: 126290-87-7
ethyl 1-acetylcyclobutanecarboxylate

: 504-63-2
trimethyleneglycol

Guidance literature:: With tetraethylammonium perchlorate; In N,N-dimethyl-formamide; electrolysis;
DOI:10.1246/cl.1987.2235

Reference yield:

: 1075-81-6
Cyclobutan-1,1-dicarbonsaeure-ethylester-chlorid

: 917-54-4
methyllithium

: 126290-87-7
ethyl 1-acetylcyclobutanecarboxylate

Guidance literature:: methyllithium; With copper(l) iodide; In tetrahydrofuran; diethyl ether; at -25 ℃; for 1h;

ethyl 1-chlorocarbonylcyclobutanecarboxylate; In tetrahydrofuran; diethyl ether; at -25 ℃; for 1.5h;
DOI:10.1021/jo0346499

Reference yield:

: 3779-29-1
diethyl cyclobutane-1,1-dicarboxylate

: 126290-87-7
ethyl 1-acetylcyclobutanecarboxylate

Guidance literature:: Multi-step reaction with 3 steps

1.1: 94 percent / KOH / H₂O; ethanol / 40 h / 0 °C

2.1: SOCl₂ / 3 h / 50 °C

3.1: CuI / diethyl ether; tetrahydrofuran / 1 h / -25 °C

3.2: 34.68 g / diethyl ether; tetrahydrofuran / 1.5 h / -25 °C

With potassium hydroxide; copper(l) iodide; thionyl chloride; In tetrahydrofuran; diethyl ether; ethanol; water;
DOI:10.1021/jo0346499