(4R,5S)-(+)-cis-4,5-Diphenyl-2-oxazolidinone

Base Information

Chemical Name:(4R,5S)-(+)-cis-4,5-Diphenyl-2-oxazolidinone
CAS No.:86286-50-2
Molecular Formula:C15H13NO2
Molecular Weight:239.274
Hs Code.:29029090
European Community (EC) Number:623-039-0
DSSTox Substance ID:DTXSID40446504
Nikkaji Number:J411.757C
Wikidata:Q82265164
Mol file:86286-50-2.mol

Synonyms:86286-50-2;(4R,5S)-(+)-cis-4,5-Diphenyl-2-oxazolidinone;(4R,5S)-cis-4,5-Diphenyloxazolidin-2-one;(4R,5S)-4,5-DIPHENYLOXAZOLIDIN-2-ONE;(4R,5S)-4,5-Diphenyl-1,3-oxazolidin-2-one;2-Oxazolidinone, 4,5-diphenyl-, cis-;SCHEMBL2798313;DTXSID40446504;MFCD00674023;AKOS015917416;4alpha,5alpha-Diphenyloxazolidin-2-one;4,5-Diphenyl-1,3-oxazolidin-2-one #;AS-43483;(4r,5s)-4,5-dipheny-loxazolidin-2-one;2-oxazolidinone,4,5-diphenyl-,(4R,5S)-;A841599;(4R,5S)-(+)-cis-4,5-Diphenyl-2-oxazolidinone, 98%;InChI=1/C15H13NO2/c17-15-16-13(11-7-3-1-4-8-11)14(18-15)12-9-5-2-6-10-12/h1-10,13-14H,(H,16,17)/t13-,14+/m1/s

Suppliers and Price of (4R,5S)-(+)-cis-4,5-Diphenyl-2-oxazolidinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
(4R,5S)-(+)-cis-4,5-Diphenyl-2-oxazolidinone 98%
1g
$ 148.00

Crysdot
(4R,5S)-cis-4,5-Diphenyloxazolidin-2-one 95+%
5g
$ 432.00

Chemenu
(4R,5S)-4,5-diphenyloxazolidin-2-one 95%
5g
$ 408.00

American Custom Chemicals Corporation
(4R,5S)-(+)-CIS-4,5-DIPHENYL-2-OXAZOLIDINONE 95.00%
1G
$ 744.02

Ambeed
(4R,5S)-cis-4,5-Diphenyloxazolidin-2-one 95+%
5g
$ 518.00

Total 18 raw suppliers

Chemical Property of (4R,5S)-(+)-cis-4,5-Diphenyl-2-oxazolidinone

Chemical Property:

Vapor Pressure:6.98E-09mmHg at 25°C
Melting Point:227-230 °C(lit. )
Refractive Index:1.59
Boiling Point:466.6 °C at 760 mmHg
PKA:11.56±0.60(Predicted)
Flash Point:236 °C
PSA：38.33000
Density:1.192 g/cm³;
LogP:3.53760
XLogP3:2.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:239.094628657
Heavy Atom Count:18
Complexity:293

Purity/Quality:

97% ^*data from raw suppliers

(4R,5S)-(+)-cis-4,5-Diphenyl-2-oxazolidinone 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2C(OC(=O)N2)C3=CC=CC=C3
Isomeric SMILES:C1=CC=C(C=C1)[C@@H]2[C@@H](OC(=O)N2)C3=CC=CC=C3

Technology Process of (4R,5S)-(+)-cis-4,5-Diphenyl-2-oxazolidinone

There total 58 articles about (4R,5S)-(+)-cis-4,5-Diphenyl-2-oxazolidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: ((1R,2S)-2-Hydroxy-1,2-diphenyl-ethyl)-urea

: 86286-50-2
(4R,5S)-4,5-diphenyl-1,3-oxazolidin-2-one

Guidance literature:: With hydrogenchloride; water; sodium nitrite; at 20 ℃; for 0.0833333h;
DOI:10.1055/s-2000-6508

Reference yield: 97.0%

: 23364-44-5
(1S,2R)-2-Amino-1,2-diphenylethanol

: 503-38-8
trichloromethyl chloroformate

: 86286-50-2
(4R,5S)-4,5-diphenyl-1,3-oxazolidin-2-one

Guidance literature:: With triethylamine; In dichloromethane;
DOI:10.1016/S0040-4039(00)92670-4

Reference yield: 96.0%

: 23364-44-5
(1S,2R)-2-Amino-1,2-diphenylethanol

: 124-38-9,18923-20-1
carbon dioxide

: 86286-50-2
(4R,5S)-4,5-diphenyl-1,3-oxazolidin-2-one

Guidance literature:: (1S,2R)-2-Amino-1,2-diphenylethanol; carbon dioxide; With 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetonitrile; at 20 ℃; for 0.75h;

With tributylphosphine; di-tert-butyl-diazodicarboxylate; In acetonitrile; at 0 ℃; for 0.333333h;
DOI:10.1021/ol0491080