dimethyl (3R)-5-methyl-3-phenyl-3,4-dihydro-1H-pyrrolo[1,2-a]thiazole-6,7-dicarboxylate

Base Information

Chemical Name:dimethyl (3R)-5-methyl-3-phenyl-3,4-dihydro-1H-pyrrolo[1,2-a]thiazole-6,7-dicarboxylate
CAS No.:158446-64-1
Molecular Formula:C₁₇H₁₇NO₄S
Molecular Weight:331.392
Hs Code.:

Synonyms:dimethyl (3R)-5-methyl-3-phenyl-3,4-dihydro-1H-pyrrolo[1,2-a]thiazole-6,7-dicarboxylate

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Chemical Property of dimethyl (3R)-5-methyl-3-phenyl-3,4-dihydro-1H-pyrrolo[1,2-a]thiazole-6,7-dicarboxylate

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Technology Process of dimethyl (3R)-5-methyl-3-phenyl-3,4-dihydro-1H-pyrrolo[1,2-a]thiazole-6,7-dicarboxylate

There total 2 articles about dimethyl (3R)-5-methyl-3-phenyl-3,4-dihydro-1H-pyrrolo[1,2-a]thiazole-6,7-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.5%

: 196930-46-8
(4R)-2-phenyl-1,3-thiazolidine-4-carboxylic acid

: 108-24-7
acetic anhydride

: 762-42-5
dimethyl acetylenedicarboxylate

: 158446-64-1
dimethyl (3R)-5-methyl-3-phenyl-3,4-dihydro-1H-pyrrolo[1,2-a]thiazole-6,7-dicarboxylate

Guidance literature:: at 95 - 100 ℃; for 4h;
DOI:10.1016/S0040-4020(00)00243-X

Reference yield: 75.0%

: 196930-46-8
(4R)-2-phenyl-1,3-thiazolidine-4-carboxylic acid

: 874008-12-5
3-Hexin-1,6-dicarbonsaeure-dimethylester

: 158446-64-1
dimethyl (3R)-5-methyl-3-phenyl-3,4-dihydro-1H-pyrrolo[1,2-a]thiazole-6,7-dicarboxylate

Guidance literature:: With acetic anhydride; Heating;
DOI:10.1016/j.ejmech.2010.07.029

Reference yield: 45.0%

: 158446-64-1
dimethyl (3R)-5-methyl-3-phenyl-3,4-dihydro-1H-pyrrolo[1,2-a]thiazole-6,7-dicarboxylate

: 1252613-16-3
(3R)-6,7-bis (hydroxymethyl)-5-methyl-3-phenyl-1H,3H-pyrrolo [1,2-c]thiazole

Guidance literature:: With lithium aluminium tetrahydride; In diethyl ether; dichloromethane; at 0 ℃; Reflux;
DOI:10.1016/j.ejmech.2010.07.029