(S)-methyl 2-benzyl-3-((3R,4R)-3,4-dimethyl-4-(3-(trifluoromethyl-sulfonyloxy)phenyl)piperidin-1-yl)propanoate

Base Information

Chemical Name:(S)-methyl 2-benzyl-3-((3R,4R)-3,4-dimethyl-4-(3-(trifluoromethyl-sulfonyloxy)phenyl)piperidin-1-yl)propanoate
CAS No.:762299-98-9
Molecular Formula:C₂₅H₃₀F₃NO₅S
Molecular Weight:513.578
Hs Code.:

Synonyms:(S)-methyl 2-benzyl-3-((3R,4R)-3,4-dimethyl-4-(3-(trifluoromethyl-sulfonyloxy)phenyl)piperidin-1-yl)propanoate

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Chemical Property of (S)-methyl 2-benzyl-3-((3R,4R)-3,4-dimethyl-4-(3-(trifluoromethyl-sulfonyloxy)phenyl)piperidin-1-yl)propanoate

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Technology Process of (S)-methyl 2-benzyl-3-((3R,4R)-3,4-dimethyl-4-(3-(trifluoromethyl-sulfonyloxy)phenyl)piperidin-1-yl)propanoate

There total 1 articles about (S)-methyl 2-benzyl-3-((3R,4R)-3,4-dimethyl-4-(3-(trifluoromethyl-sulfonyloxy)phenyl)piperidin-1-yl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 37595-74-7
N,N-phenylbistrifluoromethane-sulfonimide

: 170098-29-0
methyl (αS,3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-α-(phenylmethyl)-1-piperidinepropanoate

: 762299-98-9
(S)-methyl 2-benzyl-3-((3R,4R)-3,4-dimethyl-4-(3-(trifluoromethyl-sulfonyloxy)phenyl)piperidin-1-yl)propanoate

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; Product distribution / selectivity;

Reference yield: 75.3%

: 762299-98-9
(S)-methyl 2-benzyl-3-((3R,4R)-3,4-dimethyl-4-(3-(trifluoromethyl-sulfonyloxy)phenyl)piperidin-1-yl)propanoate

: 201230-82-2
carbon monoxide

: 1257642-47-9
(S)-methyl 2-benzyl-3-((3R,4R)-4-(3-carbamoylphenyl)-3,4-dimethylpiperidin-1-yl)propanoate

Guidance literature:: With 1,1,1,3,3,3-hexamethyl-disilazane; 1,3-bis-(diphenylphosphino)propane; palladium diacetate; palladium dichloride; In N,N-dimethyl-formamide; at 80 - 90 ℃; Product distribution / selectivity; Inert atmosphere;

Reference yield: 51.0%

: 762299-98-9
(S)-methyl 2-benzyl-3-((3R,4R)-3,4-dimethyl-4-(3-(trifluoromethyl-sulfonyloxy)phenyl)piperidin-1-yl)propanoate

: 201230-82-2
carbon monoxide

: 762300-00-5
C₂₆H₃₃NO₄

Guidance literature:: With triethylamine; 1,1'-bis-(diphenylphosphino)ferrocene; palladium diacetate; In methanol; dimethyl sulfoxide; at 65 ℃;