(H-D-CYS-OME)2 2 HCL

Base Information

• Chemical Name: (H-D-CYS-OME)2 2 HCL
• CAS No.: 144000-36-2
• Molecular Formula: C₈H₁₆N₂O₄S₂*2ClH
• Molecular Weight: 341.28
• Mol file: 144000-36-2.mol

Synonyms:D-Cystine,dimethyl ester, dihydrochloride (9CI)

Chemical Property of (H-D-CYS-OME)2 2 HCL

Chemical Property:

• PSA: 155.24000
• LogP: 2.37300
• Storage Temp.: Store at 0°C
• Solubility.: Methanol (Slightly), Water (Slightly)

Purity/Quality:

99% ^*data from raw suppliers

D-CystineDimethylEsterDihydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: D-Cystine Dimethyl Ester Dihydrochloride is an amino acid derivative used as a reagent.

Technology Process of (H-D-CYS-OME)2 2 HCL

There total 1 articles about (H-D-CYS-OME)2 2 HCL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

methanol (67-56-1) + S,S-cystine (349-46-2) → l-cystine dimethyl ester dihydrochloride (18598-59-9,22888-38-6,32854-09-4,110970-86-0,144000-36-2)

Guidance literature:

With thionyl chloride; at 0 - 20 ℃;

Reference yield:

trityl chloride (76-83-5) + l-cystine dimethyl ester dihydrochloride (18598-59-9,22888-38-6,32854-09-4,110970-86-0,144000-36-2) → N,N'-ditrityl-D-cystine dimethyl ester (18598-60-2,144000-37-3)

Guidance literature:

With triethylamine; In chloroform; for 24h; Ambient temperature;

Reference yield:

N-tert-butoxycarbonyl-L-phenylalanine (13734-34-4) + l-cystine dimethyl ester dihydrochloride (18598-59-9,22888-38-6,32854-09-4,110970-86-0,144000-36-2) → (S)-2-((S)-2-tert-Butoxycarbonylamino-3-phenyl-propionylamino)-3-[(S)-2-((S)-2-tert-butoxycarbonylamino-3-phenyl-propionylamino)-2-methoxycarbonyl-ethyldisulfanyl]-propionic acid methyl ester

Guidance literature:

With 4-methyl-morpholine; dicyclohexyl-carbodiimide; In chloroform; at 20 ℃;

DOI:10.1021/jo000738z

upstream raw materials:

methanol

S,S-cystine

Downstream raw materials:

N,N'-ditrityl-D-cystine dimethyl ester

Refernces

• 1、 Ten Cate, A. Tessa,Dankers, Patricia Y. W.,Kooijman, Huub,Spek, Anthony L.,Sijbesma, Rint P.,Meijer. "Enantioselective cyclization of racemic supramolecular polymers". . p. 6860 - 6861. Retrieved 2007/10/03.