N,N-dimethylmorpholine-2-carboxamide

Base Information

Chemical Name:N,N-dimethylmorpholine-2-carboxamide
CAS No.:135072-23-0
Molecular Formula:C7H14N2O2
Molecular Weight:158.2
Hs Code.:2934999090
DSSTox Substance ID:DTXSID00607634
Mol file:135072-23-0.mol

Synonyms:N,N-dimethylmorpholine-2-carboxamide;135072-23-0;N,N-Dimethyl-2-morpholinecarboxamide;2-Morpholinecarboxamide,N,N-dimethyl-(9CI);SCHEMBL2918828;DTXSID00607634;BLBLRJCALSOJFU-UHFFFAOYSA-N;MFCD11977241;AKOS011005393;CS-0444847;G50605;EN300-6769770;F1913-0333

Suppliers and Price of N,N-dimethylmorpholine-2-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N,N-dimethyl-2-morpholinecarboxamide
10mg
$ 45.00

Matrix Scientific
N,N-Dimethylmorpholine-2-carboxamide 97%
1g
$ 598.00

Crysdot
N,N-Dimethylmorpholine-2-carboxamide 95+%
1g
$ 574.00

Chemenu
N,N-Dimethylmorpholine-2-carboxamide 95%
1g
$ 542.00

Atlantic Research Chemicals
N,N-Dimethylmorpholine-2-carboxamide 95%
250mgs:
$ 140.68

Alichem
N,N-Dimethylmorpholine-2-carboxamide
5g
$ 3350.00

Alichem
N,N-Dimethylmorpholine-2-carboxamide
1g
$ 1286.74

AK Scientific
N,N-Dimethylmorpholine-2-carboxamide
1g
$ 857.00

Activate Scientific
N,N-Dimethylmorpholine-2-carboxamide 95+%
5 g
$ 1427.00

Activate Scientific
N,N-Dimethylmorpholine-2-carboxamide 95+%
250 mg
$ 261.00

Total 14 raw suppliers

Chemical Property of N,N-dimethylmorpholine-2-carboxamide

Chemical Property:

Vapor Pressure:0.003mmHg at 25°C
Refractive Index:1.464
Boiling Point:287.192 °C at 760 mmHg
PKA:7.92±0.40(Predicted)
Flash Point:127.489 °C
PSA：41.57000
Density:1.065 g/cm³
LogP:-0.60820
Storage Temp.:2-8°C
XLogP3:-1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:158.105527694
Heavy Atom Count:11
Complexity:147

Purity/Quality:

99%, ^*data from raw suppliers

N,N-dimethyl-2-morpholinecarboxamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)C(=O)C1CNCCO1

Technology Process of N,N-dimethylmorpholine-2-carboxamide

There total 2 articles about N,N-dimethylmorpholine-2-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.9%

: 135072-18-3
4-benzyl-N,N-dimethylmorpholine-2-carboxamide

: 135072-23-0
N,N-dimethylmorpholine-2-carboxamide

Guidance literature:: With ammonium formate; palladium-on-charcoal; In ethanol; at 50 ℃; for 2h;

Reference yield:

: 135072-15-0
4-benzylmorpholine-2-carboxylic acid hydrochloride

: 135072-23-0
N,N-dimethylmorpholine-2-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: oxalyl dichloride / N,N-dimethyl-formamide / 1,2-dichloro-ethane / 3 h / 65 °C

1.2: 4 h / 0 - 20 °C

2.1: ammonium formate / palladium-on-charcoal / ethanol / 2 h / 50 °C

With oxalyl dichloride; ammonium formate; palladium-on-charcoal; N,N-dimethyl-formamide; In ethanol; 1,2-dichloro-ethane;

Reference yield: 42.3%

: 108-36-1
1,3-dibromobenzene

: 135072-23-0
N,N-dimethylmorpholine-2-carboxamide

: 1416776-21-0
4-(3-Bromophenyl)-N,N-dimethylmorpholine-2-carboxamide

Guidance literature:: With sodium t-butanolate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; In toluene; at 80 ℃; for 5h; Inert atmosphere;