(2S,3R,4E)-3-O-benzoyl-N-trifluoroacetyl-1-O-trityl-4-sphingenine

Base Information

• Chemical Name: (2S,3R,4E)-3-O-benzoyl-N-trifluoroacetyl-1-O-trityl-4-sphingenine
• CAS No.: 131105-37-8
• Molecular Formula: C₄₆H₅₄F₃NO₄
• Molecular Weight: 741.934
• Mol file: 131105-37-8.mol

Synonyms:(2S,3R,4E)-3-O-benzoyl-N-trifluoroacetyl-1-O-trityl-4-sphingenine

Chemical Property of (2S,3R,4E)-3-O-benzoyl-N-trifluoroacetyl-1-O-trityl-4-sphingenine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2S,3R,4E)-3-O-benzoyl-N-trifluoroacetyl-1-O-trityl-4-sphingenine

There total 3 articles about (2S,3R,4E)-3-O-benzoyl-N-trifluoroacetyl-1-O-trityl-4-sphingenine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

(2S,3R,4E)-N-trifluoroacetyl-1-O-trityl-4-sphingenine (131105-36-7) + benzoyl chloride (98-88-4) → (2S,3R,4E)-3-O-benzoyl-N-trifluoroacetyl-1-O-trityl-4-sphingenine (131105-37-8)

Guidance literature:

With pyridine; for 18h; Ambient temperature;

Reference yield:

trityl chloride (76-83-5) → (2S,3R,4E)-3-O-benzoyl-N-trifluoroacetyl-1-O-trityl-4-sphingenine (131105-37-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 89 percent / pyridine / 14 h / 45 °C

2: 93 percent / pyridine / 18 h / Ambient temperature

With pyridine;

Reference yield:

N-[(2S,3R,E)-1,3-dihydroxyoctadec-4-en-2-yl]-2,2,2-trifluoroacetamide (130967-71-4) → (2S,3R,4E)-3-O-benzoyl-N-trifluoroacetyl-1-O-trityl-4-sphingenine (131105-37-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 89 percent / pyridine / 14 h / 45 °C

2: 93 percent / pyridine / 18 h / Ambient temperature

With pyridine;

upstream raw materials:

(2S,3R,4E)-N-trifluoroacetyl-1-O-trityl-4-sphingenine

benzoyl chloride

trityl chloride

N-[(2S,3R,E)-1,3-dihydroxyoctadec-4-en-2-yl]-2,2,2-trifluoroacetamide

Downstream raw materials:

(2S,3R,4E)-3-O-benzoyl-N-trifluoroacetyl-4-sphingenine

Glucosylsphingosine

(2S,3R,4E)-3-O-benzoyl-1-O-(tetra-O-acetyl-β-D-glucopyranosyl)-N-trifluoroacetyl-4-sphingenine