2,5-Dichloroisonicotinic acid

Base Information

Chemical Name:2,5-Dichloroisonicotinic acid
CAS No.:88912-26-9
Molecular Formula:C6H3Cl2NO2
Molecular Weight:192.001
Hs Code.:29339900
European Community (EC) Number:679-892-4
DSSTox Substance ID:DTXSID10371117
Nikkaji Number:J1.537.724K
Wikidata:Q72466592
Mol file:88912-26-9.mol

Synonyms:2,5-Dichloroisonicotinic acid;88912-26-9;2,5-dichloropyridine-4-carboxylic Acid;2,5-dichloro-4-pyridinecarboxylic acid;2,5-dichloro-isonicotinic acid;MFCD00466640;4-PYRIDINECARBOXYLIC ACID, 2,5-DICHLORO-;2,5-Dichloroisonicotinicacid;SCHEMBL1300053;GFOVTTQVBDEYPP-UHFFFAOYSA-;DTXSID10371117;GFOVTTQVBDEYPP-UHFFFAOYSA-N;BBL102333;STL556133;AKOS005070293;AB06268;AC-3586;CS-W002633;SY007561;AM20061596;D2599;FT-0610317;EN300-93715;2,5-Dichloropyridine-4-carboxylic acid, 95%;3W-0027;J-507318;Z1255450473;2,5-dichloroisonicotinic acid;2,5-DICHLORO-ISONICOTINIC ACID;InChI=1/C6H3Cl2NO2/c7-4-2-9-5(8)1-3(4)6(10)11/h1-2H,(H,10,11)

Suppliers and Price of 2,5-Dichloroisonicotinic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,5-Dichloroisonicotinic Acid
100mg
$ 45.00

TCI Chemical
2,5-Dichloroisonicotinic Acid >98.0%(T)(GC)
5g
$ 277.00

TCI Chemical
2,5-Dichloroisonicotinic Acid >98.0%(T)(GC)
500mg
$ 36.00

SynQuest Laboratories
2,5-Dichloroisonicotinic acid
250 mg
$ 35.00

SynQuest Laboratories
2,5-Dichloroisonicotinic acid
1 g
$ 54.00

SynChem
2,5-Dichloroisonicotinic acid 95+%
5 g
$ 48.00

SynChem
2,5-Dichloroisonicotinic acid 95+%
1 g
$ 19.00

Sigma-Aldrich
2,5-Dichloropyridine-4-carboxylic acid 95%
1g
$ 70.00

Oakwood
2,5-Dichloroisonicotinic Acid 97%
250mg
$ 9.00

Matrix Scientific
2,5-Dichloroisonicotinic acid 98%
25g
$ 127.00

Total 90 raw suppliers

Chemical Property of 2,5-Dichloroisonicotinic acid

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:236-238 °C
Refractive Index:1.606
Boiling Point:406.014 °C at 760 mmHg
PKA:1.49±0.25(Predicted)
Flash Point:199.35 °C
PSA：50.19000
Density:1.612 g/cm³
LogP:2.08660
Storage Temp.:Keep in dark place,Sealed in dry,Room Temperature
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:190.9540837
Heavy Atom Count:11
Complexity:165

Purity/Quality:

99% ^*data from raw suppliers

2,5-Dichloroisonicotinic Acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36/37/39-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C(=CN=C1Cl)Cl)C(=O)O

Technology Process of 2,5-Dichloroisonicotinic acid

There total 2 articles about 2,5-Dichloroisonicotinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 16110-09-1
2,5 dichloropyridine

: 124-38-9,18923-20-1
carbon dioxide

: 88912-26-9
2,5-dichloro-4-pyridinecarboxylic acid

Guidance literature:: 2,5 dichloropyridine; With n-butyllithium; N,N,N',N'',N'''-pentamethyldiethylenetriamine; In tetrahydrofuran; hexane; at -75 ℃; for 2h;

carbon dioxide; at -78 ℃;
DOI:10.1002/1099-0690(200104)2001:7<1371::AID-EJOC1371>3.0.CO;2-E

Reference yield:

: 4-Cyclohexyl-1-(2,6-dichloro-pyridin-4-yl)-2,6,7-trioxabicyclo[2.2.2]octane

: 88912-26-9
2,5-dichloro-4-pyridinecarboxylic acid

Guidance literature:

Reference yield: 93.3%

: 1273318-66-3
8-amino-1-(4-methoxyphenyl)-4,5-dihydro-1H-benzo[g]indazole-3-carboxamide

: 88912-26-9
2,5-dichloro-4-pyridinecarboxylic acid

: 1273318-67-4
8-(2,5-dichloroisonicotinamido)-1-(4-methoxyphenyl)-4,5-dihydro-1H-benzo[g]indazole-3-carboxamide

Guidance literature:: With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 23 ℃; for 3h;
DOI:10.1016/j.bmc.2010.12.027