3-HYDROXYUNDECANOIC ACID

Base Information

• Chemical Name: 3-HYDROXYUNDECANOIC ACID
• CAS No.: 40165-88-6
• Molecular Formula: C₁₁H₂₂O₃
• Molecular Weight: 202.294
• Mol file: 40165-88-6.mol

Synonyms:3-Hydroxyundecanoicacid;b-Hydroxyundecanoic acid;

Chemical Property of 3-HYDROXYUNDECANOIC ACID

Chemical Property:

• Boiling Point: 333.2 °C at 760 mmHg
• Flash Point: 169.5 °C
• PSA: 57.53000
• Density: 0.998 g/cm³
• LogP: 2.57260

Purity/Quality:

98%Min ^*data from raw suppliers

rac-3-HydroxyundecanoicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 3-Hydroxyundecanoic acid is part of a group of hydroxy acids found in Antarctic lake sediments. 3-Hydroxyundecanoic acid is also being investigated as an antimicrobial agent, having practical applications in many areas such as hospitals, and in cosmetic formulations.

Technology Process of 3-HYDROXYUNDECANOIC ACID

There total 10 articles about 3-HYDROXYUNDECANOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

(R)-3-hydroxyundecanenitrile (198561-31-8) → 3R-3-hydroxy-undecanoic acid (40165-88-6,66997-62-4,97961-62-1)

Guidance literature:

With hydrogenchloride; In dichloromethane; at 100 ℃; for 12h;

Reference yield: 53.0%

undecylenic acid (112-37-8) → 3R-3-hydroxy-undecanoic acid (40165-88-6,66997-62-4,97961-62-1)

Guidance literature:

With potassium chloride; dihydrogen peroxide; In ethanol; at 20 ℃; for 0.75h; pH=7; stereoselective reaction; Catalytic behavior; Enzymatic reaction;

DOI:10.1021/acscatal.1c03292

Reference yield:

3-oxoundecanoic acid (4435-85-2) → 3R-3-hydroxy-undecanoic acid (40165-88-6,66997-62-4,97961-62-1)

Guidance literature:

With potassium dihydrogenphosphate; baker's yeast; D-glucose; In water; at 28 ℃; for 9h; Yield given;

DOI:10.1021/jo00299a041

upstream raw materials:

nonan-1-al

ethyl bromoacetate

oct-1-ene

carbon dioxide

Downstream raw materials:

3R-3-hydroxy-undecanoic acid