2-Aminobicyclo[2.2.1]heptane-2-carboxylic acid

Base Information

Chemical Name:2-Aminobicyclo[2.2.1]heptane-2-carboxylic acid
CAS No.:20448-79-7
Molecular Formula:C₈H₁₃NO₂
Molecular Weight:155.197
Hs Code.:2922499990
DSSTox Substance ID:DTXSID10942624
Nikkaji Number:J236.628B
Wikidata:Q27074943
ChEMBL ID:CHEMBL2074957
Mol file:20448-79-7.mol

Synonyms:2-amino-2-carboxy-bicyclo-2,2,1-heptane;2-aminobicyclo(2,2,1)heptane-2-carboxylic acid;2-aminobicyclo(2,2,1)heptane-2-carboxylic acid, (1R-endo)-isomer;2-aminobicyclo(2,2,1)heptane-2-carboxylic acid, (1R-exo)-isomer;2-aminobicyclo(2,2,1)heptane-2-carboxylic acid, (1S-endo)-isomer;2-aminobicyclo(2,2,1)heptane-2-carboxylic acid, (1S-exo)-isomer;2-aminobicyclo(2,2,1)heptane-2-carboxylic acid, (endo)-isomer;2-aminobicyclo(2,2,1)heptane-2-carboxylic acid, (exo)-isomer;2-aminobicyclo(2,2,1)heptane-2-carboxylic acid, 11C-labeled;2-aminobicyclo(2,2,1)heptane-2-carboxylic acid, endo-(+-)-isomer;2-aminobicyclo(2,2,1)heptane-2-carboxylic acid, exo-(+-)-isomer;2-aminonorbornane-2-carboxylic acid;b-BCH

Suppliers and Price of 2-Aminobicyclo[2.2.1]heptane-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
BCH
50mg
$ 290.00

Tocris
BCH
50
$ 71.00

Sigma-Aldrich
2-Amino-2-norbornanecarboxylic acid amino acid transport inhibitor
100mg
$ 93.50

Sigma-Aldrich
2-Amino-2-norbornanecarboxylic acid amino acid transport inhibitor
1g
$ 532.00

Sigma-Aldrich
2-Amino-2-norbornanecarboxylic acid amino acid transport inhibitor
250mg
$ 177.00

Medical Isotopes, Inc.
2-Amino-2-norbornanecarboxylic acid
250 mg
$ 1040.00

Medical Isotopes, Inc.
2-Amino-2-norbornanecarboxylic acid
100 mg
$ 680.00

CSNpharm
BCH
5mg
$ 79.00

CSNpharm
BCH
10mg
$ 140.00

Cayman Chemical
BCH ≥98%
25mg
$ 25.00

Total 18 raw suppliers

Chemical Property of 2-Aminobicyclo[2.2.1]heptane-2-carboxylic acid

Chemical Property:

Vapor Pressure:0.000369mmHg at 25°C
Melting Point:>300 °C(lit.)
Refractive Index:1.559
Boiling Point:295.5 °C at 760 mmHg
PKA:2.58±0.20(Predicted)
Flash Point:32.5 °C
PSA：63.32000
Density:1.256 g/cm³
LogP:1.28880
Storage Temp.:Keep in dark place,Sealed in dry,Room Temperature
Solubility.:Aqueous Acid (Slightly)
XLogP3:-1.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:155.094628657
Heavy Atom Count:11
Complexity:204

Purity/Quality:

97% ^*data from raw suppliers

BCH ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2CC1CC2(C(=O)O)N
Uses 2-Amino-2-norbornanecarboxylic Acid functions in the suppressive effect of I-type amino acid transporter 1 inhibition as therapeutic target on human esophageal squamous cell carcinoma. Also use in the design and preparation of KMH-233, selective and slowly reversible inhibitor of L-type amino acid transporter 1 (LAT1) which potentiates antiproliferative drug efficacy in cancer cells

Technology Process of 2-Aminobicyclo[2.2.1]heptane-2-carboxylic acid

There total 22 articles about 2-Aminobicyclo[2.2.1]heptane-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: