(S)-3-(4-Acetylphenyl)-4-isopropyloxazolidin-2-one

Base Information

Chemical Name:(S)-3-(4-Acetylphenyl)-4-isopropyloxazolidin-2-one
CAS No.:572923-19-4
Molecular Formula:C₁₄H₁₇NO₃
Molecular Weight:247.294
Hs Code.:
DSSTox Substance ID:DTXSID30478839
Wikidata:Q82312478
Mol file:572923-19-4.mol

Synonyms:572923-19-4;(S)-3-(4-Acetylphenyl)-4-isopropyloxazolidin-2-one;3-(4-nitrophenyl)propionaldehyde;DTXSID30478839;MFCD08437104;2-Oxazolidinone,3-(4-acetylphenyl)-4-(1-methylethyl)-,(4S)-;(4S)-3-(4-Acetylphenyl)-4-(propan-2-yl)-1,3-oxazolidin-2-one

Suppliers and Price of (S)-3-(4-Acetylphenyl)-4-isopropyloxazolidin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(S)-3-(4-ACETYLPHENYL)-4-ISOPROPYLOXAZOLIDIN-2-ONE 95.00%
5MG
$ 502.05

Total 5 raw suppliers

Chemical Property of (S)-3-(4-Acetylphenyl)-4-isopropyloxazolidin-2-one

Chemical Property:

Vapor Pressure:5.91E-06mmHg at 25°C
Boiling Point:379.3°C at 760 mmHg
PKA:-2.80±0.40(Predicted)
Flash Point:183.2°C
PSA：46.61000
Density:1.149g/cm³
LogP:2.93540
XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:247.12084340
Heavy Atom Count:18
Complexity:332

Purity/Quality:

99% ^*data from raw suppliers

(S)-3-(4-ACETYLPHENYL)-4-ISOPROPYLOXAZOLIDIN-2-ONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C1COC(=O)N1C2=CC=C(C=C2)C(=O)C
Isomeric SMILES:CC(C)[C@H]1COC(=O)N1C2=CC=C(C=C2)C(=O)C

Technology Process of (S)-3-(4-Acetylphenyl)-4-isopropyloxazolidin-2-one

There total 6 articles about (S)-3-(4-Acetylphenyl)-4-isopropyloxazolidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 17016-83-0,17016-84-1,95530-58-8,103723-70-2
4-isopropyloxazolidin-2-one

: 99-90-1
para-bromoacetophenone

: 914222-93-8,572923-19-4
3-(4-acetylphenyl)-4-isopropyloxazolidin-2-one

Guidance literature:: With copper(l) iodide; dimethylaminoacetic acid; potassium carbonate; In N,N-dimethyl-formamide; at 120 ℃; for 24h; Inert atmosphere;
DOI:10.1016/j.tetlet.2012.05.081

Reference yield: 87.0%

: 13329-40-3
4-Iodoacetophenone

: 154669-57-5
(S)-ethyl (1-hydroxy-3-methylbutan-2-yl)carbamate

: 572923-19-4
(S)-3-(4-acetylphenyl)-4-isopropyloxazolidin-2-one

Guidance literature:: With copper(l) iodide; 2,2,6,6-tetramethylheptane-3,5-dione; caesium carbonate; In acetonitrile; at 20 - 100 ℃; for 20h;
DOI:10.1021/ol502322c

Reference yield: 61.0%

: 99-91-2
para-chloroacetophenone

: 17016-83-0
(4S)-4-isopropyl-1,3-oxazolidin-2-one

: 572923-19-4
(S)-3-(4-acetylphenyl)-4-isopropyloxazolidin-2-one

Guidance literature:: With tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; caesium carbonate; johnphos; In toluene; at 115 ℃; for 17h;
DOI:10.1021/ol034428p