1-(N-acetylamino)cyclohexylcarboxylic acid

Base Information

Chemical Name:1-(N-acetylamino)cyclohexylcarboxylic acid
CAS No.:4854-47-1
Molecular Formula:C₉H₁₅NO₃
Molecular Weight:185.223
Hs Code.:

Synonyms:1-(N-acetylamino)cyclohexylcarboxylic acid

Suppliers and Price of 1-(N-acetylamino)cyclohexylcarboxylic acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 5 raw suppliers

Chemical Property of 1-(N-acetylamino)cyclohexylcarboxylic acid

Chemical Property:

Purity/Quality:: 97% ^*data from raw suppliers

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Technology Process of 1-(N-acetylamino)cyclohexylcarboxylic acid

There total 8 articles about 1-(N-acetylamino)cyclohexylcarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.5%

: 1-[N-acetyl-N-(4-methoxybenzyl)amino]cyclohexylcarboxylic acid cyclohexylamide

: 4854-47-1
1-(N-acetylamino)cyclohexylcarboxylic acid

Guidance literature:: With trifluoroacetic acid; for 0.25h; Neat (no solvent); Reflux;
DOI:10.1016/j.tet.2009.09.022

Reference yield:

: 17191-43-4
1-{[(benzyloxy)carbonyl]amino}cyclohexanecarboxylic acid

: 4854-47-1
1-(N-acetylamino)cyclohexylcarboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 2 h / 20 °C / Inert atmosphere

2: tetrahydrofuran / 1.33 h / -78 - 20 °C / Inert atmosphere

With oxalyl dichloride; N,N-dimethyl-formamide; In tetrahydrofuran; dichloromethane;
DOI:10.1021/ol500523n

Reference yield:

: 115951-16-1
1-tert-butoxycarbonylaminocyclohexanecarboxylic acid

: 4854-47-1
1-(N-acetylamino)cyclohexylcarboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: phosphorus trichloride / dichloromethane / 1 h / 0 - 20 °C / Inert atmosphere

2: tetrahydrofuran / 1.33 h / -78 - 20 °C / Inert atmosphere

With phosphorus trichloride; In tetrahydrofuran; dichloromethane;
DOI:10.1021/ol500523n