8-benzyl-2-((1-methyl-1H-imidazol-2-yl)methyl)-6-phenylimidazo[1,2-a]pyrazin-3(7H)-one

Base Information

Chemical Name:8-benzyl-2-((1-methyl-1H-imidazol-2-yl)methyl)-6-phenylimidazo[1,2-a]pyrazin-3(7H)-one
CAS No.:1374302-49-4
Molecular Formula:C₂₄H₂₁N₅O
Molecular Weight:395.464
Hs Code.:

Synonyms:8-benzyl-2-((1-methyl-1H-imidazol-2-yl)methyl)-6-phenylimidazo[1,2-a]pyrazin-3(7H)-one

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Chemical Property of 8-benzyl-2-((1-methyl-1H-imidazol-2-yl)methyl)-6-phenylimidazo[1,2-a]pyrazin-3(7H)-one

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Technology Process of 8-benzyl-2-((1-methyl-1H-imidazol-2-yl)methyl)-6-phenylimidazo[1,2-a]pyrazin-3(7H)-one

There total 5 articles about 8-benzyl-2-((1-methyl-1H-imidazol-2-yl)methyl)-6-phenylimidazo[1,2-a]pyrazin-3(7H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1374302-58-5
C₁₁H₁₈N₂O₃

: 70217-86-6
2-amino-3-benzyl-5-phenyl-pyrazine

: 1374302-49-4
8-benzyl-2-((1-methyl-1H-imidazol-2-yl)methyl)-6-phenylimidazo[1,2-a]pyrazin-3(7H)-one

Guidance literature:: C₁₁H₁₈N₂O₃; 2-amino-3-benzyl-5-phenyl-pyrazine; With hydrogenchloride; water; In ethanol; at 100 ℃; for 1.5h; microwave irradiation;

With sodium hydrogencarbonate; In ethanol; ethyl acetate;

Reference yield:

: 122-78-1
phenylacetaldehyde

: 1374302-49-4
8-benzyl-2-((1-methyl-1H-imidazol-2-yl)methyl)-6-phenylimidazo[1,2-a]pyrazin-3(7H)-one

Guidance literature:: Multi-step reaction with 4 steps

1.1: sodium hydrogensulfite / water; tetrahydrofuran / 0.33 h

1.2: 1 h / 60 °C

1.3: 2 h / 0 - 30 °C

2.1: pyridine; titanium tetrachloride / 3 h / -20 - 80 °C

3.1: hydrogen / Raney Ni / ethanol; water / 120 h / 760.05 Torr

4.1: hydrogenchloride; water / ethanol / 1.5 h / 100 °C / microwave irradiation

With pyridine; hydrogenchloride; water; hydrogen; titanium tetrachloride; sodium hydrogensulfite; Raney Ni; In tetrahydrofuran; ethanol; water;

Reference yield:

: 532-54-7
oxo-phenyl-acetaldehyde oxime

: 1374302-49-4
8-benzyl-2-((1-methyl-1H-imidazol-2-yl)methyl)-6-phenylimidazo[1,2-a]pyrazin-3(7H)-one

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine; titanium tetrachloride / 3 h / -20 - 80 °C

2: hydrogen / Raney Ni / ethanol; water / 120 h / 760.05 Torr

3: hydrogenchloride; water / ethanol / 1.5 h / 100 °C / microwave irradiation

With pyridine; hydrogenchloride; water; hydrogen; titanium tetrachloride; Raney Ni; In ethanol; water;