1-(1H-indol-3-yl)ethanol

Base Information

• Chemical Name: 1-(1H-indol-3-yl)ethanol
• CAS No.: 103205-15-8
• Molecular Formula: C10H11 N O
• Molecular Weight: 161.203
• DSSTox Substance ID: DTXSID80452482
• Mol file: 103205-15-8.mol

Synonyms:1-(1H-indol-3-yl)ethanol;103205-15-8;INDOLE-3-METHYLCARBINOL;1-(1H-INDOL-3-YL)-ETHANOL;1H-Indole-3-methanol,a-methyl-;indol-3-yl ethanol;Indole-3-methyl carbinol;SCHEMBL735351;DTXSID80452482;1-(1H-indol-3-yl)ethan-1-ol;AKOS006294426;AM806324;FT-0692191;I-3200

Chemical Property of 1-(1H-indol-3-yl)ethanol

Chemical Property:

• Boiling Point: 347.2±17.0 °C(Predicted)
• PKA: 15.17±0.20(Predicted)
• PSA: 36.02000
• Density: 1.212±0.06 g/cm3(Predicted)
• LogP: 2.22120
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 161.084063974
• Heavy Atom Count: 12
• Complexity: 160

Purity/Quality:

99% ^*data from raw suppliers

1-(1H-Indol-3-yl)ethanol 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C1=CNC2=CC=CC=C21)O

Technology Process of 1-(1H-indol-3-yl)ethanol

There total 2 articles about 1-(1H-indol-3-yl)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-acetylindole (703-80-0) → 1-indol-3-yl-ethanol (103205-15-8)

Guidance literature:

With tetrahydrofuran; lithium borate;

Reference yield:

Indole-3-carboxaldehyde (487-89-8,1228547-52-1) + methylmagnesium bromide (75-16-1) → 1-indol-3-yl-ethanol (103205-15-8)

Guidance literature:

In tetrahydrofuran; at 20 ℃; for 1h;

DOI:10.1002/chem.202004232

Reference yield:

1-indol-3-yl-ethanol (103205-15-8) + sodium 4-methylbenzenesulfinate (824-79-3) → 3-(1-tosylethyl)-1H-indole (77978-07-5)

Guidance literature:

With toluene-4-sulfonic acid; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1002/chem.202004232

upstream raw materials:

3-acetylindole

Indole-3-carboxaldehyde

methylmagnesium bromide

Downstream raw materials:

3-(1-tosylethyl)-1H-indole