(S)-2-methoxy-3-(4-nitrophenyl)propanoic acid methyl ester

Base Information

• Chemical Name: (S)-2-methoxy-3-(4-nitrophenyl)propanoic acid methyl ester
• CAS No.: 1021692-54-5
• Molecular Formula: C₁₁H₁₃NO₅
• Molecular Weight: 239.228
• Mol file: 1021692-54-5.mol

Synonyms:(S)-2-methoxy-3-(4-nitrophenyl)propanoic acid methyl ester

Chemical Property of (S)-2-methoxy-3-(4-nitrophenyl)propanoic acid methyl ester

Chemical Property:

• Melting Point: 147 °C
• Boiling Point: 362.5±27.0 °C(Predicted)
• Density: 1.234±0.06 g/cm3(Predicted)

Purity/Quality:

98% ^*data from raw suppliers

(S)-Methyl2-methoxy-3-(4-nitrophenyl)propanoate 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-2-methoxy-3-(4-nitrophenyl)propanoic acid methyl ester

There total 1 articles about (S)-2-methoxy-3-(4-nitrophenyl)propanoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

L-(-)-3-(4-nitrophenyl)lactic acid methyl ester (929083-97-6) + methyl iodide (74-88-4) → (S)-2-methoxy-3-(4-nitrophenyl)propanoic acid methyl ester (1021692-54-5)

Guidance literature:

With silver(l) oxide; In toluene; for 5h; Reflux;

DOI:10.1016/j.ejmech.2009.03.009

Reference yield: 89.0%

(S)-2-methoxy-3-(4-nitrophenyl)propanoic acid methyl ester (1021692-54-5) → (S)-3-(4-aminophenyl)-2-methoxypropanoic acid methyl ester (933795-51-8)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In ethyl acetate; for 3h; under 3102.97 Torr;

DOI:10.1016/j.ejmech.2009.03.009

upstream raw materials:

L-(-)-3-(4-nitrophenyl)lactic acid methyl ester

methyl iodide

Downstream raw materials:

(S)-3-(4-aminophenyl)-2-methoxypropanoic acid methyl ester