cis-4-{4-[3-(4-chloro-3-trifluoromethylphenyl)ureido]cyclohexyloxy}pyridine-2-carboxylic acid tert-butyl ester

Base Information

Chemical Name:cis-4-{4-[3-(4-chloro-3-trifluoromethylphenyl)ureido]cyclohexyloxy}pyridine-2-carboxylic acid tert-butyl ester
CAS No.:1394011-94-9
Molecular Formula:C₂₄H₂₇ClF₃N₃O₄
Molecular Weight:513.944
Hs Code.:

Synonyms:cis-4-{4-[3-(4-chloro-3-trifluoromethylphenyl)ureido]cyclohexyloxy}pyridine-2-carboxylic acid tert-butyl ester

Suppliers and Price of cis-4-{4-[3-(4-chloro-3-trifluoromethylphenyl)ureido]cyclohexyloxy}pyridine-2-carboxylic acid tert-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of cis-4-{4-[3-(4-chloro-3-trifluoromethylphenyl)ureido]cyclohexyloxy}pyridine-2-carboxylic acid tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of cis-4-{4-[3-(4-chloro-3-trifluoromethylphenyl)ureido]cyclohexyloxy}pyridine-2-carboxylic acid tert-butyl ester

There total 6 articles about cis-4-{4-[3-(4-chloro-3-trifluoromethylphenyl)ureido]cyclohexyloxy}pyridine-2-carboxylic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 478832-23-4
cis-4-nitrobenzoic acid 4-(1,3-dioxo-1,3-dihydroisoindol-2-yl)cyclohexyl ester

: 1394011-94-9
cis-4-{4-[3-(4-chloro-3-trifluoromethylphenyl)ureido]cyclohexyloxy}pyridine-2-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 4 steps

1.1: hydrazine hydrate / dichloromethane; methanol / 20 °C / Inert atmosphere

2.1: triethylamine / N,N-dimethyl-formamide / 0 °C / Inert atmosphere

3.1: sodium hydroxide / tetrahydrofuran / 20 °C / Inert atmosphere

3.2: Inert atmosphere

4.1: potassium tert-butylate / tetrahydrofuran / 0 - 20 °C / Inert atmosphere

With potassium tert-butylate; hydrazine hydrate; triethylamine; sodium hydroxide; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 53750-66-6
4-chloro-pyridine-2-carbonyl chloride

: 1394011-94-9
cis-4-{4-[3-(4-chloro-3-trifluoromethylphenyl)ureido]cyclohexyloxy}pyridine-2-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / 1,2-dichloro-ethane / 0 - 50 °C / Inert atmosphere

2: potassium tert-butylate / tetrahydrofuran / 0 - 20 °C / Inert atmosphere

With pyridine; potassium tert-butylate; In tetrahydrofuran; 1,2-dichloro-ethane;

Reference yield:

: 948303-89-7
cis-4-nitro-benzoic acid 4-amino-cyclohexyl ester

: 1394011-94-9
cis-4-{4-[3-(4-chloro-3-trifluoromethylphenyl)ureido]cyclohexyloxy}pyridine-2-carboxylic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: triethylamine / N,N-dimethyl-formamide / 0 °C / Inert atmosphere

2.1: sodium hydroxide / tetrahydrofuran / 20 °C / Inert atmosphere

2.2: Inert atmosphere

3.1: potassium tert-butylate / tetrahydrofuran / 0 - 20 °C / Inert atmosphere

With potassium tert-butylate; triethylamine; sodium hydroxide; In tetrahydrofuran; N,N-dimethyl-formamide;