4-Methylpiperazine-1-carboximidamide sulfate

Base Information

• Chemical Name: 4-Methylpiperazine-1-carboximidamide sulfate
• CAS No.: 28457-20-7
• Molecular Formula: 2C₆H₁₄N₄*H₂O₄S
• Molecular Weight: 382.487
• DSSTox Substance ID: DTXSID40574336
• Mol file: 28457-20-7.mol

Synonyms:4-Methylpiperazine-1-carboximidamide sulfate;84727-42-4;4-Methyl-1-piperazinecarboximidamide sulfate;1130758-96-1;4-Methylpiperazine-1-carboximidamide sulfate(1:X);SCHEMBL2382855;DTXSID40574336;OWFBETMVTYKOTM-UHFFFAOYSA-N;MFCD01748423;BS-38988;4-methyl-piperazine-1-carboxamidine sulfate;CS-0037722;W11036;4-Methylpiperazine-1-carboximidamide monosulfate;A907394;Sulfuric acid--4-methylpiperazine-1-carboximidamide (1/1)

Chemical Property of 4-Methylpiperazine-1-carboximidamide sulfate

Chemical Property:

• Vapor Pressure: 1.64E-08mmHg at 25°C
• Boiling Point: 427.6°Cat760mmHg
• Flash Point: 212.4°C
• PSA: 195.68000
• Density: g/cm³
• LogP: 0.03420
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 1
• Exact Mass: 240.08922618
• Heavy Atom Count: 15
• Complexity: 207

Purity/Quality:

97% ^*data from raw suppliers

4-Methyl-piperazine-1-carboxamidineHemisulfate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN1CCN(CC1)C(=N)N.OS(=O)(=O)O

Technology Process of 4-Methylpiperazine-1-carboximidamide sulfate

There total 1 articles about 4-Methylpiperazine-1-carboximidamide sulfate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-methyl-piperazine (109-01-3) + S-Methylisothiourea sulfate (867-44-7,147895-43-0) → N-methylpiperazine carboxamidine sulfate (28457-20-7,84727-42-4)

Guidance literature:

In water; for 0.25h; Heating;

DOI:10.1016/j.bmcl.2005.04.011 DOI:10.1016/j.bmcl.2005.04.014

Reference yield: 93.0%

2-bromo-5-chlorobenzoic acid (21739-93-5) + N-methylpiperazine carboxamidine sulfate (28457-20-7,84727-42-4) → 6-chloro-2-(4-methylpiperazin-1-yl)quinazolin-4(3H)-one (33017-92-4)

Guidance literature:

2-bromo-5-chlorobenzoic acid; N-methylpiperazine carboxamidine sulfate; With caesium carbonate; In N,N-dimethyl-formamide; for 0.333333h; Inert atmosphere;

With copper(l) iodide; caesium carbonate; In N,N-dimethyl-formamide; at 110 ℃; for 40h; Inert atmosphere;

DOI:10.1055/s-0029-1216871

Reference yield: 84.0%

N-methylpiperazine carboxamidine sulfate (28457-20-7,84727-42-4) + 2-bromobenzoic-acid (88-65-3) → 2-(4-methylpiperazin-1-yl)quinazolin-4(3H)-one (16822-65-4)

Guidance literature:

N-methylpiperazine carboxamidine sulfate; 2-bromobenzoic-acid; With caesium carbonate; In N,N-dimethyl-formamide; for 0.333333h; Inert atmosphere;

With copper(l) iodide; caesium carbonate; In N,N-dimethyl-formamide; at 110 ℃; for 20h; Inert atmosphere;

DOI:10.1055/s-0029-1216871

upstream raw materials:

1-methyl-piperazine

S-Methylisothiourea sulfate

Downstream raw materials:

6-(2-Hydroxy-phenyl)-2-(4-methyl-piperazin-1-yl)-5-nitro-3H-pyrimidin-4-one

5-Amino-6-(2-hydroxy-phenyl)-2-(4-methyl-piperazin-1-yl)-3H-pyrimidin-4-one

4-phenyl-2-(4-methylpiperazin-1-yl)quinazoline

6-chloro-2-(4-methylpiperazin-1-yl)quinazolin-4(3H)-one

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 28457-20-7 4-METHYLPIPERAZINE-1-CARBOXAMIDINE HEMISULFATE

Send

Send

Metric Ton KG G Pound L ML

Send

Send