2-(4-Methyl-piperazin-1-yl)-4-phenyl-quinazoline

Base Information

Chemical Name:2-(4-Methyl-piperazin-1-yl)-4-phenyl-quinazoline
CAS No.:14005-52-8
Molecular Formula:C19H20N4
Molecular Weight:304.395
Hs Code.:
DSSTox Substance ID:DTXSID20425115
Nikkaji Number:J787.312C
Wikidata:Q82237871
Mol file:14005-52-8.mol

Synonyms:2-(4-Methyl-piperazin-1-yl)-4-phenyl-quinazoline;IFLab1_000976;14005-52-8;Oprea1_112573;SCHEMBL5787748;DTXSID20425115;PEKUOJUNFKUHJH-UHFFFAOYSA-N;HMS1414M08;AKOS001390023;CCG-319672;2-(4-Methylpiperazino)-4-phenylquinazoline;2-(4-methyl-1-piperazinyl)-4-phenylquinazoline;SR-01000005310;SR-01000005310-1;Z94798464

Suppliers and Price of 2-(4-Methyl-piperazin-1-yl)-4-phenyl-quinazoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 2-(4-Methyl-piperazin-1-yl)-4-phenyl-quinazoline

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:304.16879665
Heavy Atom Count:23
Complexity:374

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCN(CC1)C2=NC3=CC=CC=C3C(=N2)C4=CC=CC=C4

Technology Process of 2-(4-Methyl-piperazin-1-yl)-4-phenyl-quinazoline

There total 3 articles about 2-(4-Methyl-piperazin-1-yl)-4-phenyl-quinazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 109-01-3
1-methyl-piperazine

: 29874-83-7
2-chloro-4-phenylquinazoline

: 14005-52-8
4-phenyl-2-(4-methylpiperazin-1-yl)quinazoline

Guidance literature:: for 2h; Heating;
DOI:10.1016/S0223-5234(97)86176-4

Reference yield: 48.0%

: 13047-06-8
o-bromobenzophenone

: 28457-20-7,84727-42-4
N-methylpiperazine carboxamidine sulfate

: 14005-52-8
4-phenyl-2-(4-methylpiperazin-1-yl)quinazoline

Guidance literature:: o-bromobenzophenone; N-methylpiperazine carboxamidine sulfate; With caesium carbonate; L-proline; In N,N-dimethyl-formamide; for 0.333333h; Inert atmosphere;

With copper(l) iodide; caesium carbonate; In N,N-dimethyl-formamide; at 120 ℃; for 40h; Inert atmosphere;
DOI:10.1055/s-0029-1216871