1,2-Bis(3-chlorophenyl)disulfane

Base Information

• Chemical Name: 1,2-Bis(3-chlorophenyl)disulfane
• CAS No.: 19742-92-8
• Molecular Formula: C12H8Cl2S2
• Molecular Weight: 287.234
• DSSTox Substance ID: DTXSID50431264
• Nikkaji Number: J185.669C
• Wikidata: Q72466077
• Mol file: 19742-92-8.mol

Synonyms:19742-92-8;1,2-bis(3-chlorophenyl)disulfane;3,3'-Dichloro diphenyl disulfide;Disulfide, bis(3-chlorophenyl);1-CHLORO-3-[(3-CHLOROPHENYL)DISULFANYL]BENZENE;3,3/'-DICHLORO DIPHENYL DISULFIDE;bis(3-chlorophenyl) disulfide;bis-(3-chlorophenyl)disulfide;Di(3-chlorophenyl) persulfide;SCHEMBL225086;bis-(3-chlorophenyl) disulfide;DTXSID50431264;OLOYVIPZMIIGOH-UHFFFAOYSA-N;MFCD08460161;AKOS015898646;1,1'-Disulfanediylbis(3-chlorobenzene);AC-16502;FT-0614045;F75881;J-511062

Chemical Property of 1,2-Bis(3-chlorophenyl)disulfane

Chemical Property:

• Boiling Point: 373.388 °C at 760 mmHg
• Flash Point: 167.954 °C
• PSA: 50.60000
• Density: 1.431 g/cm³
• LogP: 5.79280
• XLogP3: 5.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 285.9444480
• Heavy Atom Count: 16
• Complexity: 191

Purity/Quality:

99% ^*data from raw suppliers

1,2-Bis(3-chlorophenyl)disulfane 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC(=C1)Cl)SSC2=CC(=CC=C2)Cl

Technology Process of 1,2-Bis(3-chlorophenyl)disulfane

There total 15 articles about 1,2-Bis(3-chlorophenyl)disulfane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

3-chlorophenylthiol (2037-31-2) → bis(3-chlorophenyl) disulfide (19742-92-8)

Guidance literature:

With silica supported cobalt(II) tetrasulfophthalocyanine; In ethyl acetate; at 20 ℃; for 1.5h;

DOI:10.1007/s00706-007-0789-9

Reference yield: 91.0%

3-iodochlorobenzene (625-99-0) → bis(3-chlorophenyl) disulfide (19742-92-8)

Guidance literature:

With indium(III) oxide; ammonia; water; sulfur; In ethanol; at 60 ℃; Green chemistry;

DOI:10.1080/00397911.2018.1466335

Reference yield: 85.0%

3-chloro-aniline (108-42-9) → bis(3-chlorophenyl) disulfide (19742-92-8)

Guidance literature:

3-chloro-aniline; With tetrafluoroboric acid; sodium nitrite; In water; acetone; at -20 - 0 ℃; for 0.333333h;

With carbon disulfide; tris(2,2-bipyridine)ruthenium(II) hexafluorophosphate; In dimethyl sulfoxide; at 20 ℃; for 6h; Concentration; Irradiation;

DOI:10.3762/bjoc.13.91

upstream raw materials:

3-chlorophenylthiol

3-chlorobenzenesulfinyl chloride

3-chlorobenzenediazonium tetrafluoroborate

[(3-chlorophenyl)sulfanyl]acetic acid

Downstream raw materials:

5-(3-chlorophenylthio)-2(1H)-pyrimidinone

1,5-bis(3-chlorophenyl)-2,4-diaza-1,3,5-trithia-2,3-pentadiene

1-((2-trimethylsilylethoxy)methyl)-6-(3-chlorophenylthio)uracil

1-ethoxymethyl-6-(3-chlorophenylthio)uracil

Refernces

• 1、 Dalapati, Rana,Sakthivel, Balasubramanian,Ghosalya, Manoj K.,Dhakshinamoorthy, Amarajothi,Biswas, Shyam. "A cerium-based metal-organic framework having inherent oxidase-like activity applicable for colorimetric sensing of biothiols and aerobic oxidation of thiols". . p. 5915 - 5925. Retrieved 2017.
• 2、 Bai, Ruoli,Barbosa, Euzébio Guimar?es,Beatriz, Adilson,Hamel, Ernest,Khodyuk, Rejane Gon?alves Diniz,Louren?o, Estela Mariana Guimar?es,de Lima, Dênis Pires,dos Santos, Edson dos Anjos. "Diaryl disulfides and thiosulfonates as combretastatin A-4 analogues: Synthesis, cytotoxicity and antitubulin activity". . . Retrieved 2020/07/07.
• 3、 Li, Xing,Du, Jia,Zhang, Yongli,Chang, Honghong,Gao, Wenchao,Wei, Wenlong. "Synthesis and nano-Pd catalyzed chemoselective oxidation of symmetrical and unsymmetrical sulfides". . p. 3048 - 3055. Retrieved 2019/03/21.