2-[(1-benzyl-1,2,3,6-tetrahydropyridin-4-yl)methoxy]-3-bromobenzonitrile

Base Information

Chemical Name:2-[(1-benzyl-1,2,3,6-tetrahydropyridin-4-yl)methoxy]-3-bromobenzonitrile
CAS No.:937254-51-8
Molecular Formula:C₂₀H₁₉BrN₂O
Molecular Weight:383.288
Hs Code.:

Synonyms:2-[(1-benzyl-1,2,3,6-tetrahydropyridin-4-yl)methoxy]-3-bromobenzonitrile

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-[(1-benzyl-1,2,3,6-tetrahydropyridin-4-yl)methoxy]-3-bromobenzonitrile

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Technology Process of 2-[(1-benzyl-1,2,3,6-tetrahydropyridin-4-yl)methoxy]-3-bromobenzonitrile

There total 1 articles about 2-[(1-benzyl-1,2,3,6-tetrahydropyridin-4-yl)methoxy]-3-bromobenzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 13073-28-4
3-bromo-2-hydroxybenzonitrile

: 158984-76-0
1,2,3,6-tetrahydro-1-(phenylmethyl)-4-pyridinemethanol

: 937254-51-8
2-[(1-benzyl-1,2,3,6-tetrahydropyridin-4-yl)methoxy]-3-bromobenzonitrile

Guidance literature:: With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 0 - 20 ℃;

Reference yield: 69.0%

: 937254-51-8
2-[(1-benzyl-1,2,3,6-tetrahydropyridin-4-yl)methoxy]-3-bromobenzonitrile

: 937254-52-9
1'-benzylspiro[1-benzofuran-3,4'-piperidine]-7-carbonitrile

Guidance literature:: 2-[(1-benzyl-1,2,3,6-tetrahydropyridin-4-yl)methoxy]-3-bromobenzonitrile; With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In toluene; for 4h; Heating / reflux;

With potassium fluoride; In diethyl ether; water;