methyl 3-(3,5-bis{bis[(pyridin-2-yl)methyl]aminomethyl}-4-hydroxyphenyl)propanoate

Base Information

• Chemical Name: methyl 3-(3,5-bis{bis[(pyridin-2-yl)methyl]aminomethyl}-4-hydroxyphenyl)propanoate
• CAS No.: 1332625-25-8
• Molecular Formula: C₃₆H₃₈N₆O₃
• Molecular Weight: 602.736
• Mol file: 1332625-25-8.mol

Synonyms:methyl 3-(3,5-bis{bis[(pyridin-2-yl)methyl]aminomethyl}-4-hydroxyphenyl)propanoate

Chemical Property of methyl 3-(3,5-bis{bis[(pyridin-2-yl)methyl]aminomethyl}-4-hydroxyphenyl)propanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 3-(3,5-bis{bis[(pyridin-2-yl)methyl]aminomethyl}-4-hydroxyphenyl)propanoate

There total 2 articles about methyl 3-(3,5-bis{bis[(pyridin-2-yl)methyl]aminomethyl}-4-hydroxyphenyl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 3-(4-hydroxyphenyl)propionic acid methyl ester (5597-50-2) + bis[(2-pyridyl)methyl]amine (1539-42-0) → methyl 3-(3,5-bis{bis[(pyridin-2-yl)methyl]aminomethyl}-4-hydroxyphenyl)propanoate (1332625-25-8)

Guidance literature:

With hydrogenchloride; In ethanol; water; for 36h; Reflux;

DOI:10.1002/asia.201100149

Reference yield:

3-(4-hydroxyphenyl)propionic acid methyl ester (5597-50-2) + bis[(2-pyridyl)methyl]amine (1539-42-0) → methyl 3-(3,5-bis{bis[(pyridin-2-yl)methyl]aminomethyl}-4-hydroxyphenyl)propanoate (1332625-25-8)

Guidance literature:

With hydrogenchloride; In ethanol; water;

Reference yield: 85.0%

methyl 3-(3,5-bis{bis[(pyridin-2-yl)methyl]aminomethyl}-4-hydroxyphenyl)propanoate (1332625-25-8) → 3-(3,5-bis((bis(pyridin-2-ylmethyl)amino)methyl)-4-hydroxyphenyl) propanoic acid (1332625-26-9)

Guidance literature:

methyl 3-(3,5-bis{bis[(pyridin-2-yl)methyl]aminomethyl}-4-hydroxyphenyl)propanoate; With sodium hydroxide; In methanol; water; at 20 ℃; for 24h;

With hydrogenchloride; In water;

DOI:10.1002/asia.201100149

upstream raw materials:

formaldehyd

3-(4-hydroxyphenyl)propionic acid methyl ester

bis[(2-pyridyl)methyl]amine

Downstream raw materials:

3-(3,5-bis((bis(pyridin-2-ylmethyl)amino)methyl)-4-hydroxyphenyl) propanoic acid