3-(2,4-DICHLORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER

Base Information

• Chemical Name: 3-(2,4-DICHLORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER
• CAS No.: 60868-41-9
• Molecular Formula: C11H10 Cl2 O3
• Molecular Weight: 261.105
• Hs Code.: 2918300090
• Mol file: 60868-41-9.mol

Synonyms:Ethyl(2,4-dichlorobenzoyl)acetate; Ethyl 2-(2,4-dichlorobenzoyl)acetate

Chemical Property of 3-(2,4-DICHLORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER

Chemical Property:

• Boiling Point: 323℃
• Flash Point: 128℃
• PSA: 43.37000
• Density: 1.319
• LogP: 3.12930
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

3-(2,4-Dichloro-phenyl)-3-oxo-propionicacidethylester ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-(2,4-DICHLORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER

There total 9 articles about 3-(2,4-DICHLORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

C17H16Cl2O3Se → ethyl 3-(2,4-dichlorophenyl)-3-oxopropionate (60868-41-9)

Guidance literature:

With dihydrogen peroxide; In tetrahydrofuran; at 20 - 50 ℃; for 3h;

DOI:10.3184/030823407X198311

Reference yield: 78.0%

hydrogen ethyl malonate (1071-46-1) + 2,4-dichlorobenzoyl chloride (89-75-8) → ethyl 3-(2,4-dichlorophenyl)-3-oxopropionate (60868-41-9)

Guidance literature:

With n-butyllithium;

DOI:10.1021/jm00014a005

Reference yield: 66.5%

→ ethyl 3-(2,4-dichlorophenyl)-3-oxopropionate (60868-41-9)

Guidance literature:

With triethylamine; magnesium chloride; In acetonitrile; at 10 ℃; for 2.5h;

In acetonitrile; at 0 ℃;

upstream raw materials:

hydrogen ethyl malonate

2,4-dichlorobenzoyl chloride

2-(2,4-dichloro-benzoyl)-3-oxo-butyric acid ethyl ester

2,4-dichlorobenzaldeyhde

Downstream raw materials:

C₁₅H₁₉Cl₂O₄PS

C₁₆H₂₁Cl₂O₄PS₂

3-(2,4-Dichloro-phenyl)-3-oxo-2-pyrrolidin-(2E)-ylidene-propionic acid ethyl ester

ethyl 2,4-dichloro-α-<(cyclopropylamino)methylene>-β-oxobenzenepropenoate