Methyl 2-[(2-methylphenyl)amino]-3-pyridinecarboxylate

Base Information

Chemical Name:Methyl 2-[(2-methylphenyl)amino]-3-pyridinecarboxylate
CAS No.:114501-03-0
Molecular Formula:C₁₄H₁₄N₂O₂
Molecular Weight:242.277
Hs Code.:
DSSTox Substance ID:DTXSID401208849

Synonyms:SCHEMBL7272538;Methyl 2-[(2-methylphenyl)amino]-3-pyridinecarboxylate;DTXSID401208849;114501-03-0

Suppliers and Price of Methyl 2-[(2-methylphenyl)amino]-3-pyridinecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of Methyl 2-[(2-methylphenyl)amino]-3-pyridinecarboxylate

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:242.105527694
Heavy Atom Count:18
Complexity:283

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=CC=C1NC2=C(C=CC=N2)C(=O)OC

Technology Process of Methyl 2-[(2-methylphenyl)amino]-3-pyridinecarboxylate

There total 4 articles about Methyl 2-[(2-methylphenyl)amino]-3-pyridinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 2-o-Tolylamino-nicotinic acid cyanomethyl ester

: 114501-03-0
2-o-Tolylamino-nicotinic acid methyl ester

Guidance literature:: With triethylamine; In methanol; for 6h; Heating;
DOI:10.1021/jm00119a010

Reference yield:

: 2942-59-8
2-chloronicotinic acid

: 114501-03-0
2-o-Tolylamino-nicotinic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 72 percent

2: triethylamine / acetone / 1.) 0 deg C, 2.) heating, 18 h

3: 80 percent / triethylamine / methanol / 6 h / Heating

With triethylamine; In methanol; acetone;
DOI:10.1021/jm00119a010

Reference yield:

: 17782-05-7
2-[(2-methylphenyl)amino]pyridine-3-carboxylic acid

: 114501-03-0
2-o-Tolylamino-nicotinic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / acetone / 1.) 0 deg C, 2.) heating, 18 h

2: 80 percent / triethylamine / methanol / 6 h / Heating

With triethylamine; In methanol; acetone;
DOI:10.1021/jm00119a010