(S)-2-Amino-3-(2-chloro-4-hydroxyphenyl)propanoic acid

Base Information

Chemical Name:(S)-2-Amino-3-(2-chloro-4-hydroxyphenyl)propanoic acid
CAS No.:70680-93-2
Molecular Formula:C₉H₁₀ClNO₃
Molecular Weight:215.636
Hs Code.:2922509090
DSSTox Substance ID:DTXSID00564596
Mol file:70680-93-2.mol

Synonyms:70680-93-2;(S)-2-Amino-3-(2-chloro-4-hydroxyphenyl)propanoic acid;2-Chloro-L-tyrosine;(2S)-2-AMINO-3-(2-CHLORO-4-HYDROXYPHENYL)PROPANOIC ACID;ortho-Chlortyrosin;SCHEMBL5580203;(S)-2-Amino-3-(2-chloro-4-hydroxyphenyl)propanoicacid;DTXSID00564596;CS-0434230;F80519

Suppliers and Price of (S)-2-Amino-3-(2-chloro-4-hydroxyphenyl)propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Chloro-L-tyrosine
250mg
$ 45.00

chempep
3-Chlorotyrosine
5g
$ 139.00

chempep
3-Chlorotyrosine
25g
$ 328.00

American Custom Chemicals Corporation
(S)-2-AMINO-3-(2-CHLORO-4-HYDROXYPHENYL)PROPANOIC ACID 95.00%
1G
$ 729.00

American Custom Chemicals Corporation
(S)-2-AMINO-3-(2-CHLORO-4-HYDROXYPHENYL)PROPANOIC ACID 95.00%
5MG
$ 498.18

AHH
3-Chlorotyrosine 97%
25g
$ 388.00

Activate Scientific
2-Chloro-L-tyrosine 95+%
250 mg
$ 233.00

Acrotein
2-Chloro-L-tyrosine 97%
1g
$ 412.50

Total 9 raw suppliers

Chemical Property of (S)-2-Amino-3-(2-chloro-4-hydroxyphenyl)propanoic acid

Chemical Property:

Melting Point:249 °C(lit.)
Boiling Point:408.9±45.0 °C(Predicted)
PKA:2.21±0.15(Predicted)
PSA：83.55000
Density:1.458±0.06 g/cm3(Predicted)
LogP:1.70030
Storage Temp.:Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility.:Aqueous Acid (Slightly), Methanol (Slightly)
XLogP3:-1.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:215.0349209
Heavy Atom Count:14
Complexity:212

Purity/Quality:

99% ^*data from raw suppliers

2-Chloro-L-tyrosine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1O)Cl)CC(C(=O)O)N
Isomeric SMILES:C1=CC(=C(C=C1O)Cl)C[C@@H](C(=O)O)N

Technology Process of (S)-2-Amino-3-(2-chloro-4-hydroxyphenyl)propanoic acid

There total 1 articles about (S)-2-Amino-3-(2-chloro-4-hydroxyphenyl)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 108-43-0
3-monochlorophenol

: 113-24-6
sodium pyruvate

: 70680-93-2
2-chloro-L-tyrosine

Guidance literature:: With recombinant tyrosine phenol lyase M₃₇₉V from Citrobacter freundii; ammonium chloride; In aq. phosphate buffer; at 21 ℃; for 24h; regioselective reaction; Enzymatic reaction;
DOI:10.1002/anie.201505696

Reference yield: 54.0%

: 70680-93-2
2-chloro-L-tyrosine

: 132574-58-4
α-D-L-2-chlorotyrosine

Guidance literature:: In water-d2; at 30 ℃; for 24h; potassium-phophate buffer, pyridoxal-5'-phosphate, lyophilized E_. coli cells containing tryptophanase, anaerobic incubation;
DOI:10.1016/S0040-4039(00)97240-X

Reference yield:

: 70680-93-2
2-chloro-L-tyrosine

: 4-(2-Amino-ethyl)-3-chloro-phenol

Guidance literature:: With NH₄OH-NH₄Cl buffer; pyridoxal 5'-phosphate; at 30 ℃; for 0.5h; relative rate of CO₂ evolution by aromatic L-amino acid decarboxylase from Micrococcus percitreus;