4-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)benzoic acid

Base Information

Chemical Name:4-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)benzoic acid
CAS No.:160977-92-4
Molecular Formula:C₂₃H₁₉NO₄
Molecular Weight:373.408
Hs Code.:2922509090
European Community (EC) Number:688-055-2
DSSTox Substance ID:DTXSID40590511
Wikidata:Q82484178
Mol file:160977-92-4.mol

Synonyms:160977-92-4;4-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)benzoic acid;N-Fmoc-4-(methylamino)benzoic acid;Fmoc-4-methylaminobenzoic acid;4-[9H-fluoren-9-ylmethoxycarbonyl(methyl)amino]benzoic acid;4-{[(9H-fluoren-9-ylmethoxy)carbonyl](methyl)amino}benzoic acid;4-({[(9H-fluoren-9-yl)methoxy]carbonyl}(methyl)amino)benzoic acid;4-[{[(9H-Fluoren-9-yl)methoxy]carbonyl}(methyl)amino]benzoic acid;SCHEMBL18170903;DTXSID40590511;4-(N-Fmoc-methylamino)benzoic acid;MFCD04972272;AKOS015910910;4-(N-Fmoc-N-methyl-amino)benzoic acid;N-FMOC-4-(METHYLAMINO)BENZOICACID;CS-0217663;EN300-81230;F93548;N-Fmoc-4-(methylamino)benzoic acid, AldrichCPR

Suppliers and Price of 4-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)benzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Medical Isotopes, Inc.
N-Fmoc-4-(methylamino)benzoicacid
5 g
$ 770.00

Medical Isotopes, Inc.
N-Fmoc-4-(methylamino)benzoicacid
1 g
$ 390.00

Matrix Scientific
Fmoc-4-methylaminobenzoic acid
1g
$ 146.00

Matrix Scientific
Fmoc-4-methylaminobenzoic acid
5g
$ 518.00

Crysdot
4-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)benzoicacid 97%
5g
$ 487.00

American Custom Chemicals Corporation
FMOC-4-METHYLAMINOBENZOIC ACID 95.00%
5G
$ 1062.60

American Custom Chemicals Corporation
FMOC-4-METHYLAMINOBENZOIC ACID 95.00%
1G
$ 247.80

Alichem
4-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)benzoicacid
1g
$ 151.51

Alichem
4-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)benzoicacid
5g
$ 444.40

Total 15 raw suppliers

Chemical Property of 4-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)benzoic acid

Chemical Property:

Boiling Point:586.6±33.0 °C(Predicted)
PKA:4.35±0.10(Predicted)
PSA：66.84000
Density:1.313±0.06 g/cm3(Predicted)
LogP:4.77010
XLogP3:4.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:373.13140809
Heavy Atom Count:28
Complexity:549

Purity/Quality:

98%min ^*data from raw suppliers

N-Fmoc-4-(methylamino)benzoicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN(C1=CC=C(C=C1)C(=O)O)C(=O)OCC2C3=CC=CC=C3C4=CC=CC=C24

Technology Process of 4-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)benzoic acid

There total 1 articles about 4-((((9H-Fluoren-9-yl)methoxy)carbonyl)(methyl)amino)benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 10541-83-0,937737-33-2
N-methyl-p-aminobenzoic acid

: 28920-43-6
(fluorenylmethoxy)carbonyl chloride

: 160977-92-4
4-((((9H-fluoren-9-yl)methoxy)carbonyl)(methyl)amino)benzoic acid

Guidance literature:: With sodium carbonate; In 1,4-dioxane; water;

Reference yield:

: 160977-92-4
4-((((9H-fluoren-9-yl)methoxy)carbonyl)(methyl)amino)benzoic acid

: (9H-fluoren-9-yl)methylmethyl(4-((3-oxo-7-phenylisoindolin-4-yl)carbamoyl)phenyl)carbamate

Guidance literature:: Multi-step reaction with 2 steps

1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 1 h / 0 - 20 °C / Inert atmosphere

2: triethylamine / dichloromethane / 0 - 20 °C / Inert atmosphere

With oxalyl dichloride; triethylamine; N,N-dimethyl-formamide; In dichloromethane;

Reference yield:

: 160977-92-4
4-((((9H-fluoren-9-yl)methoxy)carbonyl)(methyl)amino)benzoic acid

: 4-(methylamino)-N-(3-oxo-7-phenylisoindolin-4-yl)benzamide

Guidance literature:: Multi-step reaction with 3 steps

1: oxalyl dichloride; N,N-dimethyl-formamide / dichloromethane / 1 h / 0 - 20 °C / Inert atmosphere

2: triethylamine / dichloromethane / 0 - 20 °C / Inert atmosphere

3: piperidine / N,N-dimethyl-formamide / 20 °C / Inert atmosphere

With piperidine; oxalyl dichloride; triethylamine; N,N-dimethyl-formamide; In dichloromethane; N,N-dimethyl-formamide;