(2,2-dimethyl-1,3-dioxolan-4-yl)methyl acetate

Base Information

• Chemical Name: (2,2-dimethyl-1,3-dioxolan-4-yl)methyl acetate
• CAS No.: 121348-86-5
• Molecular Formula: C₈H₁₄O₄
• Molecular Weight: 174.197
• Mol file: 121348-86-5.mol

Synonyms:(2,2-dimethyl-1,3-dioxolan-4-yl)methyl acetate

Chemical Property of (2,2-dimethyl-1,3-dioxolan-4-yl)methyl acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (2,2-dimethyl-1,3-dioxolan-4-yl)methyl acetate

There total 23 articles about (2,2-dimethyl-1,3-dioxolan-4-yl)methyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

acetyl chloride (75-36-5) + (R,S)-2,2-dimethyl-1,3-dioxolane-4-methanol (100-79-8,36543-79-0) → (2,2-dimethyl-1,3-dioxolan-4-yl)methyl acetate (121348-86-5,14739-11-8)

Guidance literature:

With pyridine; dmap; In benzene; at 20 ℃; for 1h; Cooling with ice;

DOI:10.1016/j.tet.2014.06.049

Reference yield: 99.0%

acetic acid (64-19-7,77671-22-8) + (R,S)-2,2-dimethyl-1,3-dioxolane-4-methanol (100-79-8,36543-79-0) → (2,2-dimethyl-1,3-dioxolan-4-yl)methyl acetate (121348-86-5,14739-11-8)

Guidance literature:

With sodium hydrogencarbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; ethyl cyanoglyoxylate-2-oxime; In water; acetonitrile; at 20 ℃; for 2h;

DOI:10.1021/ol3022337 DOI:10.1021/ol3022337

Reference yield: 99.0%

vinyl acetate (108-05-4,9003-20-7) + (R,S)-2,2-dimethyl-1,3-dioxolane-4-methanol (100-79-8,36543-79-0) → (2,2-dimethyl-1,3-dioxolan-4-yl)methyl acetate (121348-86-5,14739-11-8)

Guidance literature:

With hexamethyltriamido-N-benzylimidophosphate; In tetrahydrofuran; at 20 ℃; for 14h;

DOI:10.1021/jo990928d

upstream raw materials:

acetic anhydride

(R,S)-2,2-dimethyl-1,3-dioxolane-4-methanol

N-acetyl-1,3-oxazol-2-one

vinyl acetate

Downstream raw materials:

(R,S)-2,2-dimethyl-1,3-dioxolane-4-methanol

(S)-(+)-(2,2-dimethyl-[1,3]dioxolan-4-yl)methanol

1,2-O-isopropylidene-D-glycerol

(2,2-dimethyl-1,3-dioxolan-4-yl)methyl acetate

Refernces

• 1、 -. "Method for synthesizing acetone ketal glycerinum acetate from glycerinum". Paragraph 0019. . Retrieved 2019/12/25.
• 2、 Dodson, Jennifer R.,Leite, Thays d C. M.,S. Pontes, Nathália,Peres Pinto, Bianca,Mota, Claudio J. A.. "Green Acetylation of Solketal and Glycerol Formal by Heterogeneous Acid Catalysts to Form a Biodiesel Fuel Additive". . p. 2728 - 2734. Retrieved 2016/12/23.