Technology Process of (E,E)-2,5-dimethoxy-1,4-bis[2-(4-(ethyl carboxylate)styryl)]benzene
There total 3 articles about (E,E)-2,5-dimethoxy-1,4-bis[2-(4-(ethyl carboxylate)styryl)]benzene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
triphenyl phosphite; potassium carbonate; bis(dibenzylideneacetone)-palladium(0);
In
N,N-dimethyl-formamide;
at 100 ℃;
for 48h;
Schlenk technique;
Inert atmosphere;
DOI:10.1080/00397911.2012.699579
- Guidance literature:
-
Multi-step reaction with 2 steps
1: sulfuric acid; potassium iodate; iodine / acetic acid; water / Reflux
2: potassium carbonate; bis(dibenzylideneacetone)-palladium(0); triphenyl phosphite / N,N-dimethyl-formamide / 48 h / 100 °C / Schlenk technique; Inert atmosphere
With
triphenyl phosphite; potassium iodate; sulfuric acid; iodine; potassium carbonate; bis(dibenzylideneacetone)-palladium(0);
In
water; acetic acid; N,N-dimethyl-formamide;
2: |Heck Reaction;
DOI:10.1080/00397911.2012.699579
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: acetonitrile / 40 h / 20 °C
2.1: ethanol / 0.17 h / Reflux
2.2: 2 h / Reflux
3.1: potassium carbonate; bis(dibenzylideneacetone)-palladium(0); triphenyl phosphite / N,N-dimethyl-formamide / 48 h / 100 °C / Schlenk technique; Inert atmosphere
With
triphenyl phosphite; potassium carbonate; bis(dibenzylideneacetone)-palladium(0);
In
ethanol; N,N-dimethyl-formamide; acetonitrile;
2.2: |Wittig Olefination / 3.1: |Heck Reaction;
DOI:10.1080/00397911.2012.699579
